cov D-dimers los ntawm degradation ntawm fibrin, ib qho protein koom nrog hauv cov ntshav txhaws.

Thaum cov ntshav txhaws, piv txwv li thaum muaj kev raug mob, qee qhov ntawm nws cov neeg koom nrog muab lawv tus kheej rau ib leeg, tshwj xeeb nrog kev pab los ntawm fibrin cov.

Thaum muaj cov ntshav txhaws tsis txaus, nws tuaj yeem ua rau cov ntshav tsis txaus (los ntshav). Ntawm qhov tsis sib xws, thaum nws yog ntau dhau, nws tuaj yeem cuam tshuam nrog kev tsim ntawm ntshav txhaws uas tej zaum yuav muaj teeb meem tshwm sim (dav vein thrombosis, pulmonary embolism). Nyob rau hauv cov ntaub ntawv no, ib tug tiv thaiv mechanism yog muab tso rau hauv qhov chaw kom degrade cov fibrin tshaj thiab txo nws mus rau tawg, ib co ntawm lawv yog D-dimers. Lawv lub xub ntiag tuaj yeem ua pov thawj rau kev tsim cov ntshav txhaws.

Tus kws kho mob yuav muab tshuaj ntsuam xyuas D-dimer yog tias nws xav tias muaj cov ntshav txhaws. Cov no tuaj yeem ua rau muaj teeb meem loj, xws li:

• a cov hlab ntsha sib sib zog nqus thrombosis (kuj hu ua sib sib zog nqus phlebitis, nws tshwm sim los ntawm kev tsim cov hlab ntsha hauv lub venous network ntawm cov ceg qis)

• pulmonary embolism (tshwm sim ntawm cov hlab ntsha tsis muaj cov hlab ntsha pulmonary)

• los yog ib tug mob stroke

Qhov ntau npaum ntawm D-dimers yog ua los ntawm cov ntshav venous, feem ntau nqa tawm ntawm qib ntawm lub luj tshib. Lawv feem ntau kuaj pom los ntawm kev siv tshuaj tiv thaiv kab mob (siv cov tshuaj tiv thaiv).

Tsis tas yuav npaj tshwj xeeb.

Qhov concentration ntawm D-dimer hauv cov ntshav yog ib txwm tsawg dua 500 µg / l (micrograms ib liter).

Qhov kev ntsuam xyuas D-dimer muaj qhov ntsuas qhov tsis zoo siab. Hauv lwm lo lus, qhov txiaj ntsig ib txwm tso cai rau kev tshem tawm ntawm kev kuaj mob ntawm cov hlab ntsha sib sib zog nqus thiab pulmonary embolism. Ntawm qhov tod tes, yog tias qib ntawm D-dimer pom tias siab, muaj qhov tsis txaus ntseeg ntawm qhov pom ntawm cov hlab ntsha uas qhia tias muaj peev xwm ua rau cov hlab ntsha sib sib zog nqus los yog pulmonary embolism. Cov txiaj ntsig no yuav tsum tau lees paub los ntawm lwm qhov kev ntsuam xyuas (tshwj xeeb yog los ntawm kev kos duab): qhov kev ntsuam xyuas yuav tsum tau txhais nrog ceev faj.

Muaj qhov tseeb ntawm qhov kev nce qib ntawm D-dimers tsis cuam tshuam rau qhov muaj cov hlab ntsha sib sib zog nqus thiab pulmonary embolism. Cia peb hais:

• cev xeeb tub

• daim siab mob

• ntshav poob

• resorption ntawm hematoma,
• kev phais tsis ntev los no

• kab mob inflammatory (xws li mob caj dab rheumatoid)

• los yog tsuas yog laus (tshaj 80)

Nco ntsoov tias qhov kev txiav txim siab ntawm D-dimers yog cov txheej txheem tsis ntev los no (txij li thaum kawg ntawm 90s), thiab cov qauv tseem yog cov lus nug. Ntau npaum li ntawd nyob rau hauv Fabkis, lub theem yog tsim raws li yuav tsum tau tsawg tshaj li 500 µg / l, whereas nyob rau hauv lub tebchaws United States qhov chaw pib yog qis dua mus rau 250 µg / l.