Hyperlymphocytosis yog ib qho txawv txav ntawm cov lymphocytes hauv cov ntshav. Nws tuaj yeem mob hnyav thaum nws ntsib thaum kis kab mob lossis mob ntev, tshwj xeeb tshaj yog thaum nws cuam tshuam nrog malignant hemopathy. Hyperlymphocytosis raug kuaj pom thaum kuaj ntshav ntau. Thiab kev kho mob nyob ntawm qhov ua rau.

Lus txhais

Hyperlymphocytosis yog qhov txawv txav ntawm cov lymphocytes hauv cov ntshav ib txwm tsawg dua 4000 lymphocytes ib cubic millimeter rau cov neeg laus.

Lymphocytes yog leukocytes (hauv lwm lo lus cov qe ntshav dawb) uas ua lub luag haujlwm tseem ceeb hauv kev tiv thaiv kab mob. Muaj peb hom lymphocytes:

• B lymphocytes: nyob rau hauv kev sib cuag nrog antigen, lawv tsim cov tshuaj tiv thaiv tshwj xeeb rau cov khoom no txawv teb chaws rau lub cev
• T lymphocytes: Qee tus ua kom cov antigens thiab cov kab mob kis tau los ntawm kev txuas mus rau lawv cov cell membranes txhaj tshuaj lom enzymes, lwm tus pab B lymphocytes ua cov tshuaj tiv thaiv kab mob, thiab lwm tus tsim cov tshuaj tiv thaiv kab mob.
• Ntuj Killer lymphocytes: lawv muaj lub ntuj cytotoxic kev ua haujlwm uas tso cai rau lawv los ua kom cov cell uas muaj kab mob los yog mob qog noj ntshav.

hom

Hyperlymphocytosis tuaj yeem yog:

• Mob thaum ntsib thaum kis kab mob;
• Mob ntev (ntev ntev tshaj li 2 lub hlis) tshwj xeeb tshaj yog thaum nws cuam tshuam nrog cov kab mob hemopathy;

Ua rau

Mob (los yog reactive) hyperlymphocytosis tuaj yeem tshwm sim los ntawm:

• Tus kab mob kis tau tus kab mob (mob qog, kab mob khaub thuas lossis kab mob mononucleosis, kab mob siab, rubella, kab mob HIV, kab mob Carl Smith);
• Qee cov kab mob, xws li tuberculosis lossis hnoos hawb pob, tuaj yeem muaj txiaj ntsig zoo ib yam;
• Noj tej yam tshuaj;
• Kev txhaj tshuaj tiv thaiv;
• Cov kab mob endocrine;
• Cov kab mob autoimmune;
• Kev haus luam yeeb;
• Kev ntxhov siab: hyperlymphocytosis tau pom nyob rau hauv cov neeg mob uas raug mob ntau yam mob, phais lossis mob plawv, lossis thaum lub cev tseem ceeb (kev yug menyuam);
• Kev phais tshem tawm ntawm tus po.

Mob hyperlymphocytosis tuaj yeem tshwm sim los ntawm:

• Leukemias, tshwj xeeb tshaj yog lymphoid leukemia;
• Lymphomas;
• Mob mob ntev, tshwj xeeb tshaj yog ntawm lub plab zom mov (Crohn's disease).

diagnostic

Hyperlymphocytosis raug kuaj pom thaum kuaj ntshav ntau yam:

• Kev suav tag nrho cov ntshav: kev sim tshuaj lom neeg uas ua rau nws muaj peev xwm txheeb xyuas cov cellular cov ntsiab lus uas ncig hauv cov ntshav (cov qe ntshav dawb, cov qe ntshav liab thiab platelets) thiab txiav txim siab qhov feem ntawm cov qe ntshav dawb sib txawv (tshwj xeeb yog cov lymphocytes);
• Thaum cov ntshav suav pom qhov nce ntawm cov lymphocytes, tus kws kho mob tshuaj xyuas ib qho qauv ntawm cov ntshav nyob rau hauv lub tshuab kuaj kab mob los txiav txim qhov morphology ntawm lymphocytes. Ib tug zoo heterogeneity nyob rau hauv lub morphology ntawm lub lymphocytes feem ntau characterizes ib tug mononucleosis syndrome, thiab lub xub ntiag ntawm lub hlwb tsis paub qab hau yog yam ntxwv ntawm tej yam leukemias los yog lymphomas;
• Thaum kawg, kev kuaj ntshav ntxiv tuaj yeem txheeb xyuas qhov tshwj xeeb ntawm lymphocyte (T, B, NK) uas tau nce ntxiv los pab txiav txim qhov ua rau.

Cov neeg txhawj xeeb

Hyperlymphocytosis cuam tshuam rau ob tus menyuam yaus uas nws ib txwm ua haujlwm tsis zoo thiab tsis tu ncua, nrog rau cov neeg laus uas nws tuaj yeem hloov pauv lossis mob ntev (lawv yog cov keeb kwm mob qog noj ntshav hauv 50% ntawm cov neeg mob).

Los ntawm nws tus kheej, qhov nce ntawm cov lymphocytes feem ntau tsis ua rau cov tsos mob. Txawm li cas los xij, hauv cov neeg uas muaj lymphoma thiab qee yam leukemias, hyperlymphocytosis tuaj yeem ua rau:

• Ua npaws ;
• Hmo ntuj tawm hws;
• Nyhav

Kev kho mob rau hyperlymphocytosis nyob ntawm nws qhov laj thawj, suav nrog:

• Kev kho mob hauv cov kab mob feem ntau ua rau mob hyperlymphocytosis;
• Tshuaj tua kab mob rau cov kab mob;
• Kev siv tshuaj khomob, lossis qee zaum stem cell transplantation, los kho cov kab mob leukemia;
• Kev tshem tawm qhov ua rau (kev ntxhov siab, haus luam yeeb)

Kev tiv thaiv tus mob hyperlymphocytosis cuam tshuam nrog kev tiv thaiv kab mob thiab kab mob uas tuaj yeem ua rau muaj teeb meem:

• Kev txhaj tshuaj, tshwj xeeb tshaj yog tiv thaiv kab mob qog, rubella, tuberculosis lossis hnoos hawb pob;
• Kev siv cov hnab looj tes niaj hnub thaum sib deev los tiv thaiv HIV.

Ntawm qhov tod tes, tsis muaj kev tiv thaiv kev tiv thaiv rau mob hyperlymphocytosis.