txheem
Kev kuaj mob ntsws cancer yuav tsum ceev, ua kom tiav thiab ua tiav. Tom qab ntawd nws tso cai rau tus kheej xaiv thiab kho kom zoo ntawm kev kho mob qog noj ntshav. Ua tsaug rau cov kev kho tshiab, qee cov neeg mob muaj lub sijhawm los txuas ntxiv lawv lub neej tsis yog los ntawm ob peb, tab sis los ntawm ntau lub hlis. Mob ntsws cancer dhau los ua kab mob ntev.
Mob ntsws cancer - kuaj mob
- Kev kuaj mob qog noj ntshav yuav tsum muaj kev koom tes ntawm ntau tus kws tshaj lij, tsis zoo li qee cov qog nqaij hlav hauv nruab nrog cev, xws li mob qog noj ntshav mis lossis melanoma, uas tau kuaj pom thiab kho feem ntau los ntawm oncologists. Mob ntsws cancer txawv qhov txawv ntawm no - hais tias Prof. dr hab. n. med. Joanna Chorostowska-Wynimko, tus thawj coj ntawm Lub Tsev Haujlwm Saib Xyuas Kev Tshawb Fawb thiab Kev Kho Mob ntawm Lub Tsev Haujlwm Tuberculosis thiab Mob ntsws hauv Warsaw.
Kev koom tes ntawm ntau tus kws tshaj lij yog qhov tseem ceeb, lub sijhawm mob siab rau kev kuaj mob thiab tom qab ntawd kev tsim nyog rau kev kho mob yog qhov tseem ceeb. - Kev kuaj mob sai sai, qhov kev kuaj pom thiab kev kuaj mob endoscopic sai dua, qhov kev ntsuam xyuas pathomorphological sai dua thiab kuaj qhov tsim nyog ntawm molecular, sai dua peb tuaj yeem muab cov neeg mob kho kom zoo. Tsis yog qhov zoo tshaj plaws, tsuas yog kev pom zoo. Nyob ntawm theem ntawm tus mob qog noj ntshav, peb yuav nrhiav kev kho, xws li nyob rau theem I-IIIA, lossis hauv kev mob ntsws cancer. Nyob rau hauv cov ntaub ntawv ntawm kev nce qib hauv zos, peb tuaj yeem siv cov kev kho mob hauv zos ua ke nrog kev kho mob, xws li kev kho mob hluav taws xob, kho kom zoo dua nrog kev siv tshuaj tiv thaiv kab mob, lossis thaum kawg kev kho mob rau cov neeg mob qog nqaij hlav cancer, ntawm no qhov kev cia siab yog txoj hauv kev kho tshiab, piv txwv li molecularly tsom. los yog tshuaj immunocompetent. Clinical oncologist, radiotherapist, surgeon yuav tsum koom nrog hauv pab pawg kws kho mob ntawm cov kws kho mob tshwj xeeb - hauv cov qog nqaij hlav thoracic - feem ntau kuj yog tus kws kho mob pulmonologist thiab tus kws kho mob tshwj xeeb hauv kev kuaj mob, piv txwv li kws kho mob radiologist - piav qhia Prof. dr hab. n. med. Dariusz M. Kowalski los ntawm Department of Lung and Thoracic Cancer ntawm National Institute of Oncology-National Research Institute in Warsaw, tus thawj tswj hwm ntawm Polish Lung Cancer Group.
Prof. Chorostowska-Wynimko ceeb toom tias ntau tus neeg mob qog noj ntshav muaj cov kab mob ua pa sib txuas. - Kuv tsis tuaj yeem xav txog qhov xwm txheej uas qhov kev txiav txim siab txog kev kho mob oncological zoo tshaj plaws ntawm tus neeg mob no yog ua tsis tau rau hauv tus account concomitant mob ntsws. Qhov no yog vim peb yuav tsim nyog rau kev kho mob phais ib tus neeg mob uas feem ntau lub ntsws noj qab haus huv tshwj tsis yog mob qog noj ntshav, thiab tus neeg mob uas muaj kab mob ua pa ntev, xws li pulmonary fibrosis lossis mob ntsws obstructive pulmonary (COPD). Thov nco ntsoov tias ob qho xwm txheej no yog qhov muaj feem pheej hmoo rau mob qog noj ntshav. Tam sim no, nyob rau hauv lub hnub nyoog ntawm kev sib kis, peb yuav muaj ntau tus neeg mob nrog COVID-19 mob ntsws ntsws - hais tias Prof. Chorostowska-Wynimko.
Cov kws tshaj lij hais txog qhov tseem ceeb ntawm kev kuaj pom zoo, ua tiav thiab ua tiav. - Txij li thaum lub sijhawm tseem ceeb heev, kev kuaj mob yuav tsum tau ua kom zoo thiab ua tau zoo, piv txwv li hauv cov chaw zoo uas tuaj yeem ua qhov kev kuaj mob tsawg kawg nkaus thiab cuam tshuam, suav nrog kev sau cov khoom siv biopsy zoo rau kev kuaj ntxiv, tsis hais cov txheej txheem siv. Xws li ib qho chaw yuav tsum tau ua haujlwm txuas nrog lub chaw zoo pathomorphological thiab molecular diagnostics center. Cov khoom siv rau kev tshawb fawb yuav tsum tau muab kev ruaj ntseg thiab xa mus tam sim ntawd, uas tso cai rau kev soj ntsuam zoo ntawm kev kuaj mob pathomorphological, thiab tom qab ntawd cov yam ntxwv ntawm caj ces. Qhov zoo tshaj plaws, lub chaw kuaj mob yuav tsum xyuas kom meej qhov ua tau zoo ib txhij ntawm kev txiav txim siab biomarker - ntseeg Prof. Chorostowska-Wynimko.
Lub luag haujlwm ntawm tus kws kho mob yog dab tsi
Yog tsis muaj kev kuaj mob pathomorphological lossis cytological, piv txwv li kuaj pom muaj cov qog nqaij hlav cancer, tus neeg mob tsis tuaj yeem tsim nyog rau kev kho mob. - Tus kws kho mob pathomorphologist yuav tsum sib txawv seb peb puas cuam tshuam nrog cov qog nqaij hlav tsis me me (NSCLC) lossis mob qog noj ntshav me (DRP), vim tias kev tswj hwm ntawm cov neeg mob nyob ntawm nws. Yog tias nws twb paub lawm tias qhov no yog NSCLC, tus kws kho mob yuav tsum txiav txim siab seb qhov subtype yog dab tsi - glandular, cell loj, squamous los yog lwm yam, vim tias nws yog ib qho tsim nyog yuav tsum tau txiav txim siab ntau yam kev ntsuam xyuas molecular, tshwj xeeb tshaj yog nyob rau hauv hom tsis muaj. -squamous cancer, txhawm rau tsim nyog rau kev kho mob molecular - ceeb toom prof. Kowalski.
Nyob rau tib lub sijhawm, kev xa cov khoom mus rau tus kws kho mob yuav tsum raug xa mus rau kev kuaj mob molecular kom tiav tag nrho cov biomarkers qhia los ntawm cov kev pab cuam tshuaj, cov txiaj ntsig uas xav tau los txiav txim siab txog kev kho kom zoo ntawm tus neeg mob. - Nws tshwm sim tias tus neeg mob tsuas yog xa mus rau qee qhov kev sim tshuaj molecular. Tus cwj pwm no tsis ncaj ncees. Kev kuaj mob ua tau zoo li no tsis tshua muaj peev xwm txiav txim siab seb yuav kho tus neeg mob zoo li cas. Muaj cov xwm txheej uas ib tus neeg theem ntawm kev kuaj mob molecular tau cog lus nyob rau hauv cov chaw sib txawv. Raws li qhov tshwm sim, cov ntaub so ntswg lossis cov khoom siv cytological tau ncig ncig tebchaws Poland, thiab lub sijhawm dhau mus. Cov neeg mob tsis muaj sijhawm, lawv yuav tsum tsis txhob tos - tswb prof. Chorostowska-Wynimko.
- Lub caij no, kev kho tshiab, xaiv kom tsim nyog, tso cai rau tus neeg mob mob ntsws cancer los ua tus kab mob ntev thiab muab nws tsis yog ob peb lub hlis ntawm lub neej, tab sis txawm ntau xyoo - ntxiv Prof. Kowalski.
- Tshawb xyuas koj qhov kev pheej hmoo ntawm kev mob qog noj ntshav. Kuaj koj tus kheej! Yuav ib pob tshawb fawb rau poj niam thiab txiv neej
Puas yog txhua tus neeg mob yuav tsum kuaj xyuas tag nrho?
Tsis yog txhua tus neeg mob yuav tsum tau ua tiav tag nrho cov kev ntsuam xyuas molecular. Nws raug txiav txim los ntawm hom mob qog noj ntshav. - Hauv non-squamous carcinoma, feem ntau yog adenocarcinoma, tag nrho cov neeg mob tsim nyog rau kev kho mob palliative yuav tsum tau kuaj xyuas tag nrho cov molecular, vim hais tias nyob rau hauv cov neeg mob cov kab mob molecular no (EGFR mutations, ROS1 thiab ALK gene rearrangements) tshwm sim ntau zaus dua li lwm yam mob ntsws cancer subtypes. . Ntawm qhov tod tes, kev ntsuam xyuas ntawm ligand rau hom 1 programmed tuag receptor, piv txwv li PD-L1, yuav tsum tau ua nyob rau hauv txhua rooj plaub ntawm NSCLC - hais tias Prof. Kowalski.
Chemoimmunotherapy yog zoo dua li kws khomob ib leeg
Thaum pib ntawm 2021, cov neeg mob uas muaj tag nrho cov NSCLC subtypes tau muab lub sijhawm kom tau txais kev kho mob tiv thaiv kab mob, tsis hais qib ntawm PD-L1 protein qhia. Pembrolizumab tuaj yeem siv tau txawm tias thaum PD-L1 qhia yog <50%. - nyob rau hauv cov xwm txheej zoo li no, ua ke nrog kev siv tshuaj khomob nrog kev siv cov platinum tebchaw thiab thib peb-tiam cytostatic tebchaw xaiv raws li cov kab mob qog noj ntshav.
- Cov txheej txheem zoo li no yeej zoo dua li kev kho mob ywj pheej - qhov sib txawv ntawm qhov ntev ntawm kev ciaj sia mus txog 12 lub hlis hauv kev pom zoo ntawm chemoimmunotherapy - hais tias prof. Kowalski. Qhov no txhais tau hais tias cov neeg mob kho nrog kev kho ua ke nyob nruab nrab ntawm 22 lub hlis, thiab cov neeg mob uas tau txais kev kho mob ib leeg tsuas yog me ntsis dhau 10 lub hlis. Muaj cov neeg mob uas, ua tsaug rau chemoimmunotherapy, nyob txawm ntau xyoo los ntawm kev siv.
Cov kev kho mob zoo li no muaj nyob rau hauv thawj kab ntawm kev kho mob thaum phais thiab chemoradiotherapy tsis tuaj yeem siv rau cov neeg mob uas muaj kab mob siab heev, piv txwv li metastases nyob deb. Cov xwm txheej ntxaws ntxaws tau muab tso rau hauv Txoj Haujlwm Tshuaj ntawm Lub Tsev Haujlwm Saib Xyuas Kev Noj Qab Haus Huv rau kev kho mob ntsws cancer (txoj haujlwm B.6). Raws li kev kwv yees, 25-35 feem pua yog cov neeg sib tw rau chemoimmunotherapy. Cov neeg mob uas muaj theem IV NSCLC.
Ua tsaug rau qhov sib ntxiv ntawm cov tshuaj immunocompetent rau chemotherapy, cov neeg mob teb zoo dua rau kev kho mob qog noj ntshav dua li cov neeg tau txais kev kho mob nkaus xwb. Qhov tseem ceeb, tom qab qhov kawg ntawm kev siv tshuaj khomob, immunotherapy raws li kev txuas ntxiv ntawm kev sib xyaw ua ke yog siv los ntawm tus neeg mob sab nraud. Qhov no txhais tau hais tias tus neeg mob tsis tas yuav mus pw hauv tsev kho mob txhua zaus lawv tau txais. Nws yeej txhim kho nws lub neej zoo.
Tsab ntawv tau tsim los ua ib feem ntawm kev sib tw "Longer Life with Cancer", siv los ntawm lub portal www.pacjentilekarz.pl.
Qhov no yuav txaus siab rau koj:
- Tshuaj lom zoo li asbestos. Koj tuaj yeem noj ntau npaum li cas thiaj li tsis ua mob rau koj tus kheej?
- Cov mob qog noj ntshav loj zuj zus. Tus lej ntawm cov neeg tuag kuj tseem loj hlob hauv tebchaws Poland
- Xws li kev kuaj mob yog qhov xav tsis thoob. Kuv yuav tsum paub dab tsi txog mob ntsws cancer?
Cov ntsiab lus ntawm medTvoiLokony lub vev xaib yog npaj los txhim kho, tsis hloov, kev sib cuag ntawm Tus Neeg Siv Lub Vev Xaib thiab lawv tus kws kho mob. Lub vev xaib no yog npaj rau kev qhia xov xwm thiab kev kawm nkaus xwb. Ua ntej ua raws li cov kev paub tshwj xeeb, tshwj xeeb tshaj yog cov lus qhia kho mob, muaj nyob hauv peb Lub Vev Xaib, koj yuav tsum sab laj nrog kws kho mob. Tus Thawj Coj yuav tsis ris tej yam tshwm sim los ntawm kev siv cov ntaub ntawv muaj nyob rau ntawm Lub Vev Xaib. Koj puas xav tau kev sab laj kev kho mob lossis e-phau ntawv? Mus rau halodoctor.pl, qhov chaw koj yuav tau txais kev pab online - sai sai, nyab xeeb thiab tsis tawm hauv koj lub tsev.