Cov tsos mob no, tshwm sim los ntawm kev tuag ntawm neurons nyob rau hauv ib feem ntawm lub hlwb, feem ntau tshwm sim txawm ua ntej teeb meem nco.
Cov kws tshawb fawb ntawm Indiana University Tsev Kawm Ntawv Tshuaj Kho Mob (Tebchaws USA) tau pom thawj zaug pom cov txheej txheem molecular hauv qab cov tsos mob neuropsychiatric uas feem ntau ua ntej qhov poob ntawm kev txawj ntse hauv Alzheimer's disease. Peb tab tom tham txog kev poob siab, kev tsis txaus siab, kev ntxhov siab, kev hloov pauv sai sai thiab nce kev chim siab.
Cov kws tshawb fawb tau tsom mus rau lub nucleus accumbens, thaj tsam ntawm lub hlwb uas ua lub luag haujlwm tseem ceeb hauv qhov khoom plig. Nws yog los ntawm cov nucleus accumbens tias cov tshuaj tiv thaiv rau kev txhawb nqa cov ntaub ntawv nyob ntawm.
Cov kws tshawb fawb tau pom tias Alzheimer's cov neeg mob muaj cov receptors hauv cov nucleus accumbens uas tso cai rau calcium nkag mus rau cov neurons. Feem ntau, yuav tsum tsis txhob muaj xws li receptors nyob rau hauv lub nucleus accumbens. Ib qho calcium ntau dhau ua rau kev tuag ntawm cov neurons thiab poob ntawm synaptic kev sib txuas ntawm lawv, uas ua rau cov tsos mob neuropsychiatric.
Raws li qhov no, cov kws tshawb fawb qhia tias lub hom phiaj thaiv cov calcium receptors hauv cov nucleus accumbens tuaj yeem tiv thaiv lossis ncua qhov pib ntawm Alzheimer's disease.
Ib qhov chaw: