Agranulocytosis yog cov ntshav txawv txav uas tshwm sim los ntawm kev ploj ntawm ib pawg ntawm leukocytes: neutrophil granulocytes. Muab lawv qhov tseem ceeb hauv kev tiv thaiv kab mob, lawv qhov ploj mus yuav tsum tau kho sai sai.

Agranulocytosis yog ib lo lus kho mob siv los hais txog cov ntshav abnormality. Nws sib haum mus rau yuav luag tag nrho ploj ntawm cov ntshav neutrophil granulocytes, yav tas los hu ua ntshav neutrophils.

Cov ntshav cov khoom no yog ib pawg ntawm leukocytes (cov qe ntshav dawb), cov qe ntshav koom nrog hauv lub cev tiv thaiv kab mob. Qhov no subclass kuj sawv cev rau feem ntau ntawm leukocytes nyob rau hauv cov ntshav. Hauv cov hlab ntsha, neutrophil granulocytes ua lub luag haujlwm tseem ceeb vim tias lawv yog lub luag haujlwm rau kev tiv thaiv lub cev txawv teb chaws thiab cov kab mob. Lawv muaj peev xwm phagocyte cov khoom no, uas yog hais kom nqus tau lawv thiaj li ua kom puas.

Agranulocytosis yog ib qho ntshav txawv txav uas tuaj yeem txheeb xyuas nrog a hemogram duab, kuj hu ua Blood Count and Formula (NFS). Qhov kev sim no muab ntau cov ntaub ntawv hais txog cov qe ntshav. Cov ntshav suav ua rau nws muaj peev xwm tshwj xeeb los txheeb xyuas ntau yam ntawm cov ntshav, uas cov neutrophil granulocytes yog ib feem.

Thaum lub sij hawm 'kev tsom xam neutrophil, ib qho txawv txav tau pom thaum qhov concentration ntawm cov hlwb tsawg dua 1700 / mm3, lossis 1,7 g / L hauv cov ntshav. Yog hais tias theem ntawm neutrophic granulocytes tsawg dhau, peb hais txog a neutropenia.

Agranulocytosis yog ib hom mob hnyav ntawm neutropenia. Nws yog tus cwj pwm los ntawm qib qis heev ntawm neutrophic granulocytes, tsawg dua 500 / mm3, lossis 0,5 g / L.

Feem ntau, agranulocytosis yog ntshav txawv txav uas tshwm sim tom qab noj cov tshuaj kho mob. Raws li lub hauv paus chiv keeb thiab cov yam ntxwv ntawm qhov anomaly, feem ntau muaj ob hom tshuaj agranulocytosis:

• mob mob agranulocytosis tshwm sim, txoj kev loj hlob ntawm uas yog vim xaiv toxicity ntawm ib tug tshuaj, uas cuam tshuam rau tsuas yog cov kab granulocytes;
• agranulocytosis tshwm sim nyob rau hauv cov ntsiab lus ntawm aplastic anemia, txoj kev loj hlob ntawm uas yog vim muaj kev tsis sib haum xeeb nyob rau hauv cov pob txha pob txha, uas yog yus muaj los ntawm ib tug depletion ntawm ob peb cov ntshav cell kab.

Hauv cov ntsiab lus ntawm aplastic anemia, nws tseem tuaj yeem paub qhov txawv ntawm ntau hom agranulocytosis. Tseeb tiag, cov kab mob ntshav no tshwm sim los ntawm kev cuam tshuam ntawm kev tsim cov qe ntshav hauv cov pob txha pob txha tuaj yeem muaj ntau lub hauv paus. Aplastic anemia tuaj yeem suav hais tias yog:

• post-chemotherapy aplastic anemia thaum ua raws li kev kho mob chemotherapy;
• mob aplastic anemia thaum tshwm sim los ntawm tej yam tshuaj.

Thaum cov tshuaj agranulocytosis tshwm sim nyob nruab nrab ntawm 64 thiab 83% ntawm cov neeg mob, cov kev txawv txav no yuav muaj lwm yam ua rau. Ntawm cov kab mob, kab mob los yog kab mob parasitic, ib qho kab mob nyob rau theem siab heev tuaj yeem ua rau cov neutrophic granulocytes depletion.

Muab lub luag haujlwm ntawm neutrophil granuclocytes hauv lub cev tiv thaiv kab mob, agranulocytosis nthuav tawm cov kab mob mus rau qhov tseem ceeb ntawm kev kis kab mob. Neutrophils tsis muaj ntau txaus los tawm tsam txoj kev loj hlob ntawm qee yam kab mob, uas tuaj yeem ua rau muaj kev cuam tshuam loj heev. sepsis, los yog sepsis, ib tug generalized kab mob los yog o ntawm lub cev.

Cov tsos mob ntawm agranulocytosis yog cov kab mob. Nws tuaj yeem pom nws tus kheej los ntawm cov kab mob sib kis hauv ntau thaj tsam ntawm lub cev nrog rau lub plab zom mov, ENT sphere, pulmonary system lossis txawm ntawm daim tawv nqaij.

Mob agranulocytosis tshwm sim tam sim ntawd thiab tshwm sim los ntawm qhov tshwm sim ntawm kub taub hau (tshaj 38,5 ° C) nrog ua daus no. Hauv cov pob txha pob txha aplasia, kev loj hlob ntawm agranulocytosis yuav maj mam zuj zus.

Agranulocytosis yog cov ntshav txawv txav uas yuav tsum tau kho sai sai kom tsis txhob muaj teeb meem. Txawm hais tias kev kho mob yuav txawv nyob ntawm qhov keeb kwm ntawm agranulocytosis, nws txoj kev tswj hwm feem ntau yog raws li:

• cais tawm hauv tsev kho mob los tiv thaiv tus neeg mob;
• pib siv tshuaj tua kab mob los kho cov kab mob;
• Kev siv cov granulocyte loj hlob yam tseem ceeb los txhawb kev tsim cov neutrophil granulocytes.