txheem
Ambroxol (Latin ambroxol) yog ib qho tshuaj mucolytic, qhov kev txiav txim ntawm kev ua raws li kev nce cov hnoos qeev los ntawm lub cev thiab txo nws cov viscosity. Colloquially, hom tshuaj no hu ua "expectorants". Lawv pab ua kom sai thiab ua haujlwm zoo dua ntawm kev ua pa ntawm cov hnoos qeev. Kev tso pa tawm ntawm txoj hlab pa ua lub luag haujlwm tseem ceeb hauv peb lub cev. Nws tiv thaiv cov mucosa los ntawm ziab tawm thiab ua kom zoo ntawm cilia ntawm cov pa epithelium. Qee lub sij hawm, txawm li cas los xij, nws tau tsim ntau heev thiab nws qhov ntom thiab viscosity nce. Qhov no tiv thaiv kev ua haujlwm zoo ntawm cilia thiab tsim cov kua qaub.
Cov tshuaj nquag thiab cov txheej txheem ntawm kev ua ntawm Ambroxol
Cov tshuaj nquag yog ambroxol hydrochloride. Nws qhov kev ua ub no ua rau muaj kev tsim cov pulmonary suffricant thiab txhim kho cilia ntawm cov pa epithelium. Ntau cov secretions thiab ntau zoo mucociliary thauj pab txhawb expectoration, xws li tshem tawm cov hnoos qeev los ntawm peb bronchi. Ambroxol kuj alleviates mob caj pas thiab txo qhov liab, thiab nws cov tshuaj loog hauv zos tau pom los ntawm kev thaiv cov sodium channels. Qhov ncauj ambroxol hydrochloride yog nqus tau sai thiab tag nrho los ntawm txoj hnyuv. Ambroxol yog kwv yees li 90% khi rau plasma proteins hauv cov neeg laus thiab 60-70% hauv cov menyuam mos thiab metabolised feem ntau hauv daim siab los ntawm glucuronidation thiab ib feem rau dibromoanthranilic acid.
Cov tshuaj muaj cov tshuaj nquag ambroxol
Tam sim no, muaj ntau yam kev npaj ntawm kev ua lag luam uas muaj cov tshuaj nquag ambroxol. Daim ntawv nrov tshaj plaws yog syrups thiab coated ntsiav tshuaj. Ambroxol kuj tuaj nyob rau hauv daim ntawv ntawm ntev-tso tsiav tshuaj, txhaj tshuaj, qhov ncauj tee, inhalation kua, effervescent ntsiav tshuaj thiab lwm yam kua qhov ncauj.
Kev siv tshuaj Ambroxol
Qhov ntau npaum ntawm cov tshuaj nruj me ntsis nyob ntawm nws daim ntawv. Qhov ntau npaum ntawm Ambroxol nyob rau hauv daim ntawv ntawm syrup, ntsiav tshuaj los yog inhalation zoo li txawv. Daim ntawv uas txuas rau lub pob ntawm cov tshuaj los yog cov lus qhia ntawm koj tus kws kho mob los yog kws muag tshuaj yuav tsum tau ua raws li nruj me ntsis raws li. Nws yuav tsum nco ntsoov tias cov tshuaj yuav tsum tsis txhob siv ua ntej yuav mus pw, vim hais tias nws ua rau expectorant reflexes.
Kev siv cov tshuaj Ambroxol
Kev siv cov tshuaj uas muaj ambroxol hydrochloride feem ntau tsuas yog txwv rau cov kab mob uas ua rau muaj cov kab mob hauv lub ntsws. Kev npaj raws li ambroxol yog siv nyob rau hauv mob thiab mob ntsws thiab kab mob bronchial, uas ua rau nyuaj expectoration ntawm nplaum thiab tuab secretions. Kuv tab tom tham txog cov kab mob xws li mob ntsws thiab mob ntsws ntev thiab cystic fibrosis. Ambroxol lozenges yog siv rau qhov mob ntawm qhov ntswg thiab caj pas. Thaum kev tswj hwm qhov ncauj ntawm Ambroxol tsis tuaj yeem, cov tshuaj xa mus rau lub cev parenterally. Feem ntau nyob rau hauv cov me nyuam mos ntxov ntxov thiab cov me nyuam mos uas muaj mob ua pa nyuaj, los tiv thaiv cov teeb meem pulmonary hauv cov neeg hauv kev saib xyuas hnyav, thiab cov neeg uas muaj kab mob pulmonary ntev los txo qhov kev pheej hmoo ntawm atelectasis.
Contraindications rau kev siv ntawm Ambroxol
Qee cov kab mob thiab kev siv cov tshuaj sib xyaw ua ke tuaj yeem txwv tsis pub siv lossis hloov cov tshuaj noj. Yog tias muaj kev tsis txaus siab lossis teeb meem, thov hu rau koj tus kws kho mob lossis tus kws muag tshuaj tam sim ntawd. Ambroxol tsis tuaj yeem siv yog tias peb tsis haum lossis tsis haum rau ib qho ntawm nws cov khoom xyaw. Ambroxol tuaj yeem ua rau bronchospasm. Kev ceev faj txog kev siv tshuaj yog pom zoo rau cov neeg uas muaj kab mob plab lossis duodenal ulcer, nyob rau hauv cov ntaub ntawv ntawm plab hnyuv, daim siab lossis lub raum tsis ua haujlwm, thiab nyob rau hauv cov ntaub ntawv ntawm bronchial ciliary clearance disorders thiab teeb meem nrog hnoos reflex. Cov neeg uas muaj fructose intolerance los yog lub qhov ncauj ulcers yuav tsum tsis txhob siv Ambroxol qhov ncauj ntsiav tshuaj. Cov tshuaj nkag mus rau hauv cov kua mis, yog li nws tsis pom zoo siv thaum pub niam mis.
Kev sib cuam tshuam nrog lwm yam tshuaj
Ambroxol yuav tsum tsis txhob noj ua ke nrog cov tshuaj uas tiv thaiv hnoos (xws li codeine). Kev siv Ambroxol nrog rau cov tshuaj tua kab mob xws li amoxicillin, cefuroxime thiab erythromycin ua rau kom cov tshuaj tua kab mob hauv bronchopulmonary secretions thiab hnoos qeev.
Sab los
Kev siv txhua yam tshuaj yuav ua rau muaj kev phiv tsis tau. Thaum noj Ambroxol, cov no yuav muaj xws li xeev siab, raws plab, ntuav, mob plab, tshwm sim anaphylactic, khaus, tawv nqaij (erythema multiforme, Stevens-Johnson syndrome, tshuaj lom epidermal necrolysis).