Anaplastic oligoastrocytoma, los yog anaplastic astrocytoma, yog ib qho mob qog nqaij hlav ntawm lub hlwb. Nws yog ntau precisely ib tug glioma, uas yog hais tias ib tug qog tshwm sim los ntawm lub paj hlwb, nyob rau hauv lub hlwb los yog tus txha caj qaum. Lub Koom Haum Saib Xyuas Kev Noj Qab Haus Huv Ntiaj Teb tau faib cov gliomas los ntawm I mus rau IV, nyob ntawm lawv cov morphology thiab qib ntawm malignancy. Anaplastic astrocytomas sawv cev rau qib III, nruab nrab ntawm qib I thiab II suav tias yog benign thiab glioblastomas (qib IV). Anaplastic astrocytoma tuaj yeem yog ib qho teeb meem ntawm benign qib II qog los yog loj hlob spontaneously. Nws muaj lub siab nyiam mus rau glioblastoma (qib IV) thiab lub neej expectancy yog nyob ib ncig ntawm ob mus rau peb lub xyoos, txawm tias kev kho mob nrog kev phais thiab radiotherapy / chemotherapy. Anaplastic astrocytomas thiab glioblastomas cuam tshuam txog 5 txog 8 ntawm 100 tus neeg hauv cov pej xeem. (000)

Feem ntau cov tsos mob ntawm anaplastic oligoastrocytoma tshwm sim los ntawm kev nce siab hauv lub hlwb, tshwm sim los ntawm cov qog nws tus kheej lossis los ntawm qhov txawv txav ntawm cov kua cerebrospinal nws ua rau. Cov tsos mob sib txawv nyob ntawm qhov chaw thiab qhov loj ntawm cov qog:

• Tsis nco qab, hloov tus cwj pwm thiab hemiplegia thaum lub qog loj hlob nyob rau hauv lub lobe frontal;
• qaug dab peg, tsis nco qab, kev sib koom tes thiab kev hais lus thaum nyob hauv lub cev ntawm lub cev;
• Kev cuam tshuam lub cev muaj zog thiab kev hnov ​​​​mob txawv txav (tingling thiab hlawv) thaum nws nyob hauv parietal lobe;
• Kev pom kev cuam tshuam thaum lub qog cuam tshuam nrog occipital lobe.

Qhov tseeb ua rau anaplastic astrocytoma tseem tsis tau paub, tab sis cov kws tshawb fawb ntseeg tias nws tshwm sim los ntawm kev sib xyaw ntawm cov noob caj noob ces thiab ib puag ncig ua rau muaj tus kab mob.

Anaplastic oligoastrocytoma yog me ntsis tshwm sim hauv cov txiv neej ntau dua li poj niam thiab feem ntau tshwm sim thaum muaj hnub nyoog 30 thiab 50. Nws yuav tsum tau sau tseg, txawm li cas los xij, tus kab mob no yuav cuam tshuam rau menyuam yaus, feem ntau ntawm 5 txog 9 xyoos. Anaplastic astrocytomas thiab multiform glioblastomas (qib III thiab IV) sawv cev kwv yees li 10% ntawm cov qog nqaij hlav thaum yau hauv nruab nrab paj hlwb (80% ntawm cov qog no yog qib I lossis II). (1)

Cov kab mob caj ces xws li neurofibromatosis hom I (Recklinghausen tus kab mob), Li-Fraumeni syndrome, thiab Bourneville tuberous sclerosis ua rau muaj kev pheej hmoo ntawm kev tsim cov kab mob anaplastic astrocytoma.

Raws li nrog ntau cov qog nqaij hlav, ib puag ncig yam xws li raug ultraviolet rays, ionizing hluav taws xob thiab qee yam tshuaj, nrog rau kev noj zaub mov tsis zoo thiab kev ntxhov siab yog suav tias yog qhov muaj feem pheej hmoo.

Kev kho mob ntawm anaplastic oligoastrocytoma nyob ntawm qhov tseem ceeb ntawm tus neeg mob, qhov chaw ntawm cov qog thiab qhov ceev ntawm nws txoj kev loj hlob. Nws suav nrog kev phais, xov tooj cua thiab kws khomob, ib leeg lossis ua ke. Thawj kauj ruam yog ua ib qho kev phais tshem tawm ntawm qhov loj ntawm cov qog raws li qhov ua tau (resection), tab sis qhov no tsis yog ib txwm ua tau vim qhov tsis tau hais los saum toj no. Tom qab kev phais, kev kho hluav taws xob thiab tej zaum yuav siv tshuaj khomob los sim tshem cov qog seem, piv txwv li yog tias cov hlwb malignant tau kis mus rau hauv lub hlwb.

Qhov kev kwv yees tau txuas nrog tus neeg mob lub xeev kev noj qab haus huv, cov yam ntxwv ntawm cov qog, thiab lub cev cov lus teb rau kev siv tshuaj khomob thiab kev kho mob hluav taws xob. Anaplastic astrocytoma muaj lub siab nyiam mus rau glioblastoma hauv li ob xyoos. Nrog rau kev kho tus qauv, lub sijhawm nyob nruab nrab ntawm cov neeg uas muaj anaplastic astrocytoma yog ob mus rau peb xyoos, uas txhais tau hais tias ib nrab ntawm lawv yuav tuag ua ntej lub sijhawm no. (2)