txheem
Lub mechanism ntawm qhov tshwm sim thiab kev loj hlob ntawm gastric ulcers tseem tsis tau to taub tag nrho. Ntawm qhov tod tes, nws tau raug pov thawj tias qhov ua txhaum ntawm tus kab mob yog ib qho kab mob tshwj xeeb - Helicobacter pylori. Thiab ntawm qhov tod tes, kev tiv thaiv muaj zog, kev noj qab haus huv txoj kev ua neej, kev noj zaub mov kom zoo thiab kev ruaj ntseg neuropsychological ntawm ib tus neeg yuav tsis tso cai rau Helicobacter pylori ntau thiab ua rau muaj kab mob peptic. Yog li ntawd, txoj hauv kev rau kev kho mob ntawm tus kab mob no yuav tsum ua kom tiav.
Kev kho mob rau plab rwj muaj xws li:
Noj ntau hom tshuaj raws li cov txheej txheem tshwj xeeb;
Ua raws li cov lus pom zoo thiab kev noj zaub mov zoo;
Kev kho ntawm lub hlwb-kev xav sphere thiab tsis lees paub tus cwj pwm phem;
Kev kho mob spa;
Kev phais mob (yog tias xav tau).
Tshuaj kho mob plab rwj yog ua los ntawm peb pawg tseem ceeb ntawm cov tshuaj:
tshuaj tua kab mob;
Histamine receptor blockers;
Proton twj tso kua mis inhibitors (PPIs).
Kev pab kho mob yog nqa tawm siv ntau hom tshuaj ntxiv:
Holinoblocker;
Antacids;
Reparants;
Anabolics;
Gastroprotectors;
Antispasmodics;
Cov tshuaj loog;
Ganglioblockers;
Antiemetics;
Cov vitamins;
Immunostimulants.
Lub tswv yim ntawm kev kho mob plab ulcer
Qhov zoo tshaj plaws yog ob-theem txheej txheem rau kev kho mob peptic ulcer:
Theem Kuv kav 7 hnub. Nyob rau lub sijhawm no, tus neeg mob tau muab tshuaj ua ke ntawm ob cov tshuaj tua kab mob, feem ntau metronidazole thiab clarithromycin, nrog rau cov tshuaj tiv thaiv proton twj tso kua mis, xws li lansoprazole. Cov tshuaj tuaj yeem hloov tau los ntawm cov tshuaj analogues ntawm kev txiav txim siab ntawm tus kws kho mob tuaj koom, qhov ntau npaum li cas kuj tau teem rau tus kheej. Lub hom phiaj ntawm thawj theem ntawm kev kho mob yog kev puas tsuaj tag nrho ntawm Helicobacter pylori, thiab hauv 95% ntawm cov neeg mob nws muaj peev xwm tiv nrog txoj haujlwm;
II theem siv sijhawm 14 hnub thiab tsuas yog yuav tsum tau yog tias Helicobacter pylori tseem pom hauv plab tom qab thawj theem. Tawm tsam cov kab mob, tandem ntawm cov tshuaj tua kab mob metronidazole + tetracycline yog siv, thiab kev kho yog ntxiv nrog ib qho ntawm cov tshuaj bismuth, nrog rau PPIs (omeprazole, rabeprazole) thiab histamine receptor blocker (ranitidine, famotidine).
Kev kho mob yuav tsum tau txais kev txhawb nqa los ntawm kev siv tshuaj tua kab mob, tshuaj tua kab mob, tshuaj tua kab mob, tshuaj tua kab mob, tshuaj tua kab mob, tshuaj tua kab mob thiab lwm yam tshuaj uas txo cov tsos mob tsis zoo ntawm lub plab rwj thiab ua kom cov txheej txheem kho kom zoo. Cov kev kho neeg pej xeem (tshuaj ntsuab decoctions thiab infusions), cov vitamins, natural extracts, xws li aloe vera, muaj txiaj ntsig zoo. Txawm li cas los xij, rau txhua yam tshuaj, koj yuav tsum sab laj nrog koj tus kws kho mob gastroenterologist.
Cov kab mob peptic ulcer yog ib tus neeg heev, muaj cov cim qhia sib txawv ntawm acidity thiab feem ntau nrog cov teeb meem los ntawm lwm yam kabmob. Tsis tas li ntawd, kev kho tshuaj tua kab mob yuav luag ib txwm muab cov kev mob tshwm sim nyob rau hauv daim ntawv ntawm digestive disorders thiab mob. Kev kho mob plab rwj yog pom zoo kom ua nyob rau hauv lub tsev kho mob raws li kev saib xyuas tas li ntawm cov kws tshaj lij.
Ua kom tiav cov npe tshuaj rau mob plab
tshuaj tua kab mob:
Clarithromycin. Semi-synthetic macrolide tshuaj tua kab mob. Ib tug xeeb leej xeeb ntxwv ntawm erythromycin, nws yog ib puas npaug ntau resistant rau kev puas tsuaj ntawm hydrochloric acid, ua kom tiav thiab nqus sai dua, zoo tis nyob rau hauv cov ntaub so ntswg thiab ib nrab-lub neej ntev. Vim li no, clarithromycin outperforms erythromycin thiab pom zoo raws li cov tshuaj tua kab mob tseem ceeb rau kev kho mob plab rwj;
Amoxicillin. Semi-synthetic tshuaj tua kab mob ntawm pab pawg penicillin. Tsis zoo li penicillin, nws muaj peev xwm tiv taus cov kua dej hauv plab, yog absorbed yuav luag tag nrho (los ntawm 93%), kis sai dua los ntawm cov ntaub so ntswg thiab kua, npog lub cev ntau dua thiab nyob twj ywm nyob rau hauv nws ntev, uas ua rau nws muaj peev xwm mus sau amoxicillin rau. peptic rwj ob zaug, thiab tsis yog plaub zaug ib hnub twg. hnub;
kev ntsuas. Antimicrobial thiab antiprotozoal tshuaj nrog ib tug dav spectrum ntawm kev ua. Ib qho ntawm cov laus tshaj plaws, feem ntau txhim khu kev qha thiab zoo tshuaj tua kab mob, belongs rau cov pab pawg neeg ntawm cov tshuaj tseem ceeb. Metronidazole yog ib qho hluavtaws analogue ntawm azomycin, tshuaj tua kab mob ntuj tsim los ntawm cov kab mob ntawm genus Streptomyces. Cov kab mob tsis zoo thiab cov protozoa cuam tshuam nrog metronidazole, vim tias nws cov 5-nitro pawg tau rov qab los. Thiab nws, nyob rau hauv lem, rhuav tshem DNA ntawm parasites thiab microbes;
Tetracycline. Ib qho tshuaj tua kab mob los ntawm pawg tetracycline. Nws muaj cov nyhuv bacteriostatic, uas yog, nws cuam tshuam kev cuam tshuam ntawm ribosomes thiab thauj RNA, vim tias cov protein synthesis los ntawm cov kab mob hlwb raug tshem tawm, thiab lawv tuag. Tetracycline yog nquag tawm tsam ntau cov kab mob gram-positive thiab gram-negative microorganisms, nrog rau feem ntau cov kab mob enterobacteria, suav nrog Helicobacter pylori.
Histamine receptor blockers:
Ranitidine. Cov tshuaj yog thib ob tiam ntawm histamine blockers. Txo cov kev ua ntawm pepsin (lub plab zom mov ua lub luag haujlwm rau kev tawg ntawm cov proteins). Normalizes pH theem hauv plab, inhibits cov synthesis ntawm hydrochloric acid. Nyob ntawm seb qhov ntau npaum li cas, nws tiv thaiv cov mucous membrane los ntawm kev puas tsuaj ntawm acidity ntau dhau rau 12-24 teev;
Nizatidine. Qhov thib ob tiam ntawm histamine III-receptor blockers. Nws suppresses nws tus kheej synthesis ntawm hydrochloric acid los ntawm cov phab ntsa ntawm lub plab, thiab tshaj synthesis provoked los ntawm acetylcholine, histamine thiab gastrin - enzymes thiab mediators. Qhov tseem ceeb txo qhov kev ua siab loj ntawm pepsin thiab ua kom pH qib hauv lub xeev ntawm lub cev muaj zog rau 12 teev tom qab noj;
Roxatidine. Qhov thib ob tiam ntawm histamine H2 receptor blockers. Nws inhibits cov kev ua ntawm pepsin, normalizes acid-base tshuav nyiaj li cas ntawm lub plab, txo qhov tso tawm ntawm hydrochloric acid los ntawm cov zaub mov, gastrin, histamine, acetylcholine, thiab tseem suppresses basal synthesis ntawm gastric kua txiv. Nws yog sai absorbed thiab ua nyob rau hauv ib teev tom qab noj. Cov nyhuv kav ntev li ntawm 12 teev mus rau ib hnub, nyob ntawm qhov ntau npaum li cas;
Famotidine. Nws kuj yog ib qho tshuaj ntawm tiam thib ob ntawm histamine H2 receptor blockers. Nws inhibits ob leeg basal thiab externally provoked secretion ntawm hydrochloric acid los ntawm lub hlwb ntawm lub plab mucosa. Yog li, nws zoo tiv thaiv tus neeg mob lub cev los ntawm qhov tsis zoo ntawm pepsin, histamine, gastrin thiab acetylcholine;
Cimetidine. Cov tshuaj yog thawj tiam ntawm histamine III-receptor blockers, tab sis tseem tsis tau poob nws qhov tseeb. Nws kuj tseem tswj hwm qib pH hauv plab kom zoo, inhibits cov synthesis ntawm hydrochloric acid thiab inhibits kev ua haujlwm ntawm pepsin enzyme. Nws raug nqi tsawg dua li cov analogues niaj hnub no, tab sis suav tias tsis muaj txiaj ntsig vim yog lub sijhawm luv luv ntawm kev ua haujlwm tas mus li (6-8 teev).
Proton twj tso kua mis inhibitors (PPIs):
Lansoprazole. Inhibitor ntawm H + -K + -ATPase - ib qho enzyme lub luag haujlwm rau kev sib pauv cov hydrogen ions. Txawm hais tias yog vim li cas rau hypersecretion ntawm hydrochloric acid, lansoprazole inhibits nws cov khoom nyob rau theem kawg, uas yog, tam sim ntawd ua ntej tso rau hauv lub plab kab noj hniav;
Omeprazole. Nws kuj inhibits qhov kev txiav txim ntawm lub twj tso kua mis proton los ntawm inhibiting cov haujlwm ntawm enzyme H + -K + -ATPase. Hydrogen ions nkag mus tsis zoo ntawm daim nyias nyias ntawm cov hlwb ntawm lub plab mucosa, thiab qhov no cuam tshuam nrog kev tsim cov kua txiv hmab txiv ntoo. Thiab nws tsis muaj teeb meem dab tsi raws nraim provokes lub hypersecretion ntawm hydrochloric acid - noj cov zaub mov los yog qhov kev txiav txim ntawm enzymes thiab mediators;
Rabeprazole. Paub zoo dua nyob rau hauv lub npe "pariet". Cov tshuaj no tsis tsuas yog inhibits qhov tso tawm ntawm hydrochloric acid, thaiv qhov kev txiav txim ntawm H + -K + -ATPase, tab sis kuj muaj kev cuam tshuam rau Helicobacter pylori, ua txhaum ntawm plab rwj. Rabeprazole pib ua ib teev tom qab noj thiab tiv thaiv cov mucous membrane txog li ob hnub ua ke;
Esomeprazole. Cov tshuaj, uas yog dextrorotatory isomer ntawm omeprazole, thiab muaj cov nyhuv zoo sib xws. Nws kuj inhibits cov synthesis ntawm hydrochloric acid nyob rau hauv lub xeem theem vim lub deterioration ntawm hydrogen pauv ntawm daim nyias nyias ntawm lub hlwb ntawm lub plab mucosa. Ua lub hauv paus tsis muaj zog, esomeprazole yog qhib rau hauv acidic ib puag ncig ntawm parietal tubules thiab inhibits qhov kev txiav txim ntawm lub twj tso kua mis proton.
Gastroprotectors, anabolic thiab reparants:
sucralfate. Cov tshuaj muaj antiulcer, adsorbing, enveloping, antacid thiab tiv thaiv kev ua haujlwm. Nws xyaum tsis cuam tshuam rau kev noj qab haus huv daim nyias nyias, thiab nyob rau hauv cov xwm txheej ntawm acidity ntawm lub plab muaj kab mob, nws tawg mus rau hauv sucrose sulfate thiab txhuas, uas tso cai rau koj los khi cov mucus proteins thiab tsim ib tug muaj zog tiv thaiv zaj duab xis nyob rau hauv qhov chaw ntawm ulceration. Tom qab noj sucralfate, lub plab phab ntsa raug tiv thaiv rau 6 teev los ntawm ntau tshaj hydrochloric acid, pepsin, pov tseg cov khoom ntawm cov kab mob phem thiab cov kua tsib pov tseg los ntawm lub txiav;
Solcoseryl. Muaj zog reparant thiab cytoprotector. Restores plab hnyuv mucosa, txhawb kev kho ntawm ulcers, txhim kho cell metabolism. Nws yog tsim los ntawm cov ntshav ntawm cov mis nyuj nyuj thiab yog ib tug hemodialysate nrog ib tug molecular hnyav ntawm 5000 D. Lub peev xwm ntawm solcoseryl tseem tsis tau to taub tag nrho, txawm li cas los xij, kev siv cov tshuaj no nyob rau theem ntawm kev kho mob ntawm plab rwj, uas yog. , tom qab lub active antimicrobial theem, muab exceptional zoo;
Enprostil thiab misoprostol - synthetic analogues ntawm prostaglandin E2 thiab E1, feem. Cov tshuaj no zoo ib yam li cov tshuaj hormones thiab tsim nyob rau hauv yuav luag tag nrho cov ntaub so ntswg ntawm tib neeg lub cev. Prostaglandins yog cov neeg kho mob ntawm kev ua xua thiab o, lawv tswj cov ntshav siab, normalize cov leeg nqaij, txo cov plab acidity thiab inhibit qhov tso tawm ntawm cov kua txiv hmab txiv ntoo;
Biogastron. Cov tshuaj nquag ntawm cov tshuaj no yog carbenoxolone, ib qho hluavtaws analogue ntawm glycyrrhizic acid. Cov kws tshawb fawb muab cov khoom tseem ceeb no los ntawm cov hauv paus licorice. Biogastron muaj cov txiaj ntsig zoo tiv thaiv kab mob thiab siv los kho cov kab mob ntawm lub qhov ncauj, txoj hlab pas thiab lub plab. Cov tshuaj no paub zoo nyob txawv teb chaws, thiab tsis tshua muaj siv nyob rau hauv Russia, txawm hais tias nws muaj peev xwm loj;
Actovegin. Siv tau zoo reparant thiab antihypoxant. Zoo li solcoseryl, nws yog tsim los ntawm cov ntshav thiab yog ib tug hemodialysate nrog ib tug molecular hnyav ntawm 5000 daltons. Ultrafiltration ua rau actovegin tuaj yeem nkag mus rau hauv cov ntaub so ntswg ntawm tes, txhim kho cov pa oxygen thiab qabzib thiab ua kom cov ntaub so ntswg puas thiab mob sai sai;
Bismuth tripotassium dicirate. Qhov zoo tshaj plaws kev npaj ntawm bismuth rau kev kho mob plab ulcers. Nyob rau hauv tej yam kev mob ntawm high acidity, nws sai sai tsim ib tug tiv thaiv zaj duab xis uas npog qhov chaw puas ntawm mucous daim nyias nyias. Tsis tas li ntawd, tripotassium bismuth dicitrate txhim kho kev tsim cov prostaglandin E2 thiab inhibits cov kev ua ntawm helicobacteria uas ua rau peptic rwj;
Amigluracil. Ib qho zoo anabolic thiab reparant. Nws accelerates cov synthesis ntawm cov proteins thiab amino acids, txhawb kev kho ntawm rwj thiab qhov txhab ntawm qhov txhab, txhim kho kev tiv thaiv thiab pab lub cev tiv thaiv kab mob ntawm nws tus kheej los ntawm enriching cov ntshav nrog lub cev tiv thaiv kab mob. Nws yog ntse siv nyob rau theem kawg ntawm kev rov qab los tom qab gastric thiab duodenal rwj;
Methyluracil. Kuj tseem yog ib qho nrov immunostimulant, anabolic thiab reparant. Stimulates synthesis ntawm leukocytes, accelerates nucleic metabolism, txhawb kev loj hlob sai thiab epithelialization ntawm puas cov ntaub so ntswg thiab mucous daim nyias nyias. Cov nyhuv anti-inflammatory ntawm methyluracil yog vim nws cov nyhuv inhibitory ntawm proteolytic enzymes. Nyob rau theem kawg ntawm kev kho mob plab ulcers, cov tshuaj pab caws pliav thiab rov ua dua tshiab ntawm tes;
Sodium oxyferriscarbon. Anti-inflammatory, analgesic thiab qhov txhab kho mob tshuaj raws li hlau nrog ntxiv ntawm sodium ntsev thiab alloxanic acid. Nws yog siv los kho cov kab mob peptic ntawm txoj hlab pas, me thiab duodenal ulcers, nrog rau cov kab mob plab;
Romazulan. Phytopreparation raws li chamomile, uas muaj ib tug complex nyhuv: relieves spasms, anesthetizes, tua microbes thiab nkoos lub kho ntawm qhov txhab thiab rwj. Romazulan tov yog siv ob qho tib si sab nraud, rau cov kab mob ntawm daim tawv nqaij, kab mob ntawm lub qhov ncauj kab noj hniav thiab urogenital cheeb tsam, thiab sab hauv, diluted nrog dej, rau kev kho mob ntawm peptic rwj thiab gastritis;
Histidine hydrochloride. Cov tshuaj yog ib qho amino acid, uas, thaum nws nkag mus rau hauv lub cev, ua rau cov tshuaj tiv thaiv decarboxylation, thiab vim li ntawd, histamine yog tsim - tus neeg nruab nrab uas muaj ntau yam cuam tshuam rau lub cev. Histamine stimulates zus tau tej cov epinephrine, excites cov nqaij du, tsub kom cov permeability ntawm phab ntsa ntawm cov hlab ntsha, tsub kom lub plawv dhia thiab ua rau lub plab ua kua ntau gastric, thiab nyob rau hauv tej yam mob plab rwj yog tsim nyog.
Cholinergic:
Gastrocepin. Cov tshuaj nquag - pirenzepine - belongs rau pawg M1-cholinergic receptor blockers, tab sis tsis zoo li atropine, tus neeg sawv cev nto moo tshaj plaws ntawm pab pawg no, nws tsis cuam tshuam rau kev ua haujlwm ntawm cholinergic receptors ntawm lub plawv, qhov muag, qog qaub ncaug thiab lwm yam kabmob, tab sis tsuas yog cuam tshuam rau lub plab mucosa, ua rau tsim cov hydrochloric acid thiab pepsinogen tsawg dua;
buscopan. Cov tshuaj muaj cov nyhuv thaiv ntawm M-cholinergic receptors ntawm lub plab, ob lub raum, lub zais zis thiab zais zis, thiab tseem ua haujlwm raws li cov tshuaj antispasmodic. Buscopan relieves spasms ntawm cov nqaij ntshiv thiab me ntsis txo cov theem ntawm kev tso tawm ntawm gastric kua txiv, uas ua rau nws ua tau kom symptomatically alleviate tus mob ntawm cov neeg mob plab rwj;
Platifillin. Nws thaiv M-cholinergic receptors ntawm lub cev hauv nruab nrog cev thiab qhov muag kwv yees li 8 npaug qis dua atropine, thiab tseem thaiv H-cholinergic receptors rau qee qhov. Yeej dhau atropine vim qhov tseeb tias nws ua rau tachycardia tsawg dua. Platifillin muaj cov nyhuv antispasmodic ntawm cov phab ntsa ntawm lub plab thiab cov hnyuv, ua kom cov hlab ntsha thiab txo cov ntshav siab;
Metacin. Nws kuj hais txog mob me dua li atropine blockers ntawm M-cholinergic receptors. Nws zoo txo cov suab nrov ntawm lub gallbladder thiab zais zis, relieves spasms thiab tshem tawm qhov mob nyob rau hauv lub plab, suppresses lub secretion ntawm gastric kua txiv, hws, qaub ncaug, thiab normalizes ntshav siab. Tsawg dua li atropine, nws ua rau tsis xav tau lub plawv dhia dhia, pupillary dilation thiab nce intraocular siab;
Etpenal. Blocker ntawm cholinergic receptors ntawm ob hom - "H" thiab "M". Ib qho tshuaj loog hauv zos muaj txiaj ntsig, nws muaj txiaj ntsig zoo rau ob qho tib si hauv nruab nrab thiab peripheral paj hlwb. Etpenal yog siv los kho cov tsos mob ntawm plab ulcers, nrog rau cov mob hawb pob bronchial thiab Parkinson tus kab mob, raws li nws relieves spasms thiab txo tremors.
Antacids:
Almagel. Adsorbent, enveloping thiab analgesic tshuaj, uas yog paub zoo rau tag nrho cov rwj. Almagel tiv thaiv lub plab mucosa los ntawm kev puas tsuaj ntawm ntau tshaj hydrochloric acid thiab pepsin, absorbs lom cov khoom pov tseg ntawm cov kab mob thiab cuam tshuam nrog kev nqus ntawm phosphates. Yog li, nws tsis kho mob plab, tab sis pab txo nws cov tsos mob thiab txo qhov kev puas tsuaj los ntawm cov txheej txheem inflammatory rau tus neeg mob lub cev tag nrho;
Maalox. Kev npaj Antacid raws li magnesium thiab aluminium hydroxides. Maalox reacts nrog hydrochloric acid thiab neutralizes nws tshaj, thiab tsis muaj re-compensating secretion. Cov tshuaj no normalizes pH theem thiab tiv thaiv lub plab mucosa, tab sis, zoo li Almagel, tsis tshem tawm heev ua rau peptic rwj;
Gastal. Ib qho ntxiv, ua ke antacid, uas, ntxiv rau magnesium thiab aluminium hydroxides, muaj magnesium carbonate. Tam sim ntawd tom qab noj, nws tso cai rau kev tswj hwm lub cev ib txwm muaj pH ntawm 3,5 hauv plab rau ob teev, vim yog qhov tsis zoo ntawm cov tshuaj hydrochloric acid ntau dhau. Lub plab rwj tsis zoo, tab sis txuag ntawm qhov mob thiab kub siab;
Phosphalugel. Kev npaj Antacid raws li aluminium phosphate. Nws muaj cov txiaj ntsig zoo thiab kav ntev dua li cov tshuaj saum toj no ntawm tib hom. Phosphalugel tsis tsuas yog neutralizes ntau tshaj hydrochloric acid, tab sis kuj inhibits cov kev ua ntawm pepsin enzyme. Nws cia siab rau cov phab ntsa ntawm lub plab, tsim kom muaj kev tiv thaiv kev tiv thaiv, tab sis nws tsis muaj kev cuam tshuam rau Helicobacter pylori, yog li nws tsuas yog siv tau rau cov tsos mob ntawm tus mob ntawm cov neeg mob peptic ulcer;
sodium bicarbonate hmoov. Baking soda yog qhov yooj yim tshaj plaws thiab pheej yig tshaj antacid. Ib qho kev daws ntawm dej qab zib pab daws qhov mob hauv siab thiab mob plab nrog gastritis thiab ulcers, thiab tseem siv los tiv thaiv acidosis los ntawm kev qaug dab peg ntawm lub cev lossis ntshav qab zib.
Antiemetics:
Motilium. Cov khoom xyaw nquag yog domperidone, qhov ntxeev ntawm dopamine. Cov tshuaj thaiv cov kev ua ntawm dopamine receptors thiab ua rau kom lub suab ntawm lub qis esophageal sphincter, accelerates lub zog ntawm cov zaub mov los ntawm lub digestive ib ntsuj av, stimulates lub motility ntawm lub plab thiab cov hnyuv. Motilium tsis muaj kev cuam tshuam rau kev tso tawm ntawm cov kua txiv hmab txiv ntoo, nws tsuas yog txo qis kev tawm tsam ntawm xeev siab thiab ntuav hauv gastritis thiab plab rwj;
Cerucal. Cov tshuaj tiv thaiv kev sib kis ntawm cov hlab ntsha impulses los ntawm cov visceral channels los ntawm dopamine receptors mus rau ntuav qhov chaw hauv lub hlwb, thiab tseem txhawb txoj hnyuv motility, ua rau cov suab nrov ntawm cov hlab ntsha qis thiab txhawb nqa lub zog txav ntawm cov zaub mov los ntawm txoj hnyuv. Yog li, txawm tias muaj cov laj thawj rau ntuav, nws tuaj yeem zam tau;
Metoclopramide. Cov tshuaj blocks dopamine thiab serotonin receptors, vim hais tias nws muaj peev xwm tsis tsuas yog yuav tsum tsis txhob ntuav tawm tsam, tab sis kuj yuav tsum tsis txhob hiccups thiab tsis txhob raws plab, uas yuav ua tau ib tug phiv ntawm tsiv zaub mov ntawm lub plab mus rau lub qhov quav sai heev. Metoclopramide tsis cuam tshuam rau kev ua haujlwm zais cia hauv ib txoj hauv kev, tab sis tseem muaj cov lus pom zoo kho mob tsis txaus tias cov tshuaj no txhawb kev kho mob ntawm plab rwj.
Antispasmodics:
Galidor. Cov tshuaj nquag - bentsiklar - myotropic antispasmodic, blocker ntawm calcium channels, serotonin receptors thiab sympathetic paj hlwb. Zoo kawg nkaus relieves spasms ntawm cov hlab ntsha thiab cov nqaij ntshiv, tsub kom lub elasticity ntawm erythrocytes, txo cov ntshav siab, tab sis tej zaum yuav me ntsis nce lub plawv dhia. Halidor nyob rau hauv ntau koob yog suav hais tias yog ib tug tranquilizer. Nrog rau plab rwj, nws tau qhia tias yog tshuaj loog;
Dibazol. Myotropic antispasmodic, benzimidazole derivative. Nws muaj cov nyhuv smoothing ntawm cov nqaij ntshiv ntawm lub cev, cov hlab ntsha thiab capillaries, normalizes ntshav siab, dilates cov hlab ntsha ntawm lub paj hlwb thiab accelerates tus kis ntawm paj hlwb impulses ntawm synapses. Nws zoo kawg nkaus relieves mob taub hau thiab mob nqaij, tab sis nws tsis kav ntev, yog li ntawd, nyob rau hauv kev kho mob ntawm lub plab ulcers, ntau tshaj thiab niaj hnub antispasmodics feem ntau yog sau;
Papaverine. Calcium channel blocker, me me myotropic antispasmodic. Nws dilates cov hlab ntsha thiab cov hlab ntsha, txo cov ntshav siab thiab cov leeg nqaij du, txo qhov mob hauv lub cev los ntawm cov leeg nqaij, tab sis tsis kav ntev thiab tsis cuam tshuam rau lub paj hlwb parasympathetic txaus kom txuag tau los ntawm qhov mob hnyav hauv plab rwj. Yog li ntawd, tam sim no, papaverine tsis yog suav hais tias yog ib qho kev txhim khu kev kho mob;
Mas-Shpa. Qhov nrov tshaj plaws antispasmodic. Cov tshuaj nquag, drotaverine, yog qhov zoo sib xws hauv cov qauv thiab cov tshuaj siv tshuaj rau papaverine, tab sis ua haujlwm ntau dua thiab ntev dua. No-Shpa tiv thaiv kev nkag ntawm calcium molecules rau hauv cov leeg nqaij du, yog li txo qhov mob hauv migraines, cov poj niam mob raws sij hawm thiab peptic ulcers. Qhov ntau ntawm daim ntawv thov ntawm No-Shpa yog qhov dav heev, thiab nws yog qhov no myotropic antispasmodic uas tau sau tseg rau hauv cov xwm txheej uas cov tshuaj anticholinergics yog contraindicated rau tus neeg mob vim li cas - cov tshuaj uas txo qhov mob zoo dua, tab sis tsis haum rau txhua tus.
Ganglioblockers:
Benzohexonium. Nws inhibits kev ua ntawm impulses ntawm ganglia (cov hlab ntsha loj) ntawm lub paj hlwb thiab parasympathetic, thiab tseem inhibits kev ua haujlwm ntawm tag nrho cov qog endocrine, nrog rau lub plab mucosa, adrenal cortex thiab pancreas. Benzohexonium yog siv los kho cov tsos mob ntawm plab ulcers, cholecystitis, bronchial hawb pob, cholelithiasis thiab ntau lwm yam kab mob;
Dimecoline. Ib tug zoo meej analogue ntawm benzohexonium. Nws muaj cov nyhuv antispasmodic tshaj tawm ntawm cov hlab ntsha, cov leeg thiab cov kab mob hauv nruab nrog cev los ntawm kev thaiv cov hlab ntsha ntawm cov hlab ntsha ntawm ganglia, yog li nws tau siv los daws qhov mob ntawm tus mob peptic rwj, pancreatitis, kab mob siab, cirrhosis, cholecystitis, cholelithiasis. Qee lub sij hawm dimecoline kuj tau muab rau cov neeg mob uas muaj cov hlab ntsha tsis tu ncua;
Camphonium. Quaternary ammonium compound. Zoo txo qhov siab, txo cov suab nrov ntawm cov hlab ntsha coronary thiab cov hlab ntsha peripheral, smoothes cov leeg ntawm cov kab mob hauv nruab nrog cev. Camphonium, zoo li tag nrho cov ganglion blockers, yog siv los kho cov tsos mob ntawm tus mob ntawm cov neeg mob plab ulcer, ntxiv rau, cov tshuaj no qee zaum raug muab rau cov neeg mob ntshav siab thiab cov neeg mob obliterating endarteritis.
Quateron. Monoquaternary ammonium compound. Nws inhibits kev ua ntawm cov hlab ntsha impulses nruab nrab ntawm lub ganglia ntawm lub paj hlwb parasympathetic zoo dua li lub siab xav, yog li ntawd nws yog siv tshwj xeeb los txo qhov mob ntawm ulcers thiab cov neeg mob uas muaj colitis. Kvateron nthuav cov hlab ntsha me me, yog li nws tsis tshua muaj tshuaj raws li cov tshuaj tiv thaiv hypertensive;
Temekhin. Nws cuam tshuam nrog kev sib kis ntawm cov hlab ntsha impulses los ntawm preganglionic mus rau postganglionic vegetative fibers, thiab vim li no, nws zoo relieves nqaij spasms thiab dilates cov hlab ntsha. Temekhin muaj txiaj ntsig zoo rau cov hlab ntsha, yog li nws muaj feem cuam tshuam rau kev mob ntshav siab tsis tu ncua thiab angina pectoris, thiab rau cov neeg mob plab ulcers nws raug sau tseg kom txo qis cov kua dej hauv plab thiab txo qhov mob tshwm sim los ntawm spastic phenomena.