Lipanthyl Supra - muaj pes tsawg leeg, kev ua, kev qhia, kev phiv. Yuav siv Lipanthyl Supra li cas?

Cov ntsiab lus pov thawj

Lipanthyl Supra yog cov tshuaj txo cov ntshav lipid. Cov tshuaj nquag hauv Lipanthyl Supra yog fenofibrate. Nyeem yuav ua li cas noj Lipanthyl Supra thiab cov kev mob tshwm sim uas nws tuaj yeem ua rau.

Lipanthyl Supra yog dab tsi?

Lipanthyl Supra (160 mg / 215 mg) yog ib qho tshuaj uas qhia rau kev siv ntxiv rau kev noj haus thiab lwm yam kev kho mob uas tsis yog tshuaj kho mob (xws li kev tawm dag zog, kev poob phaus) hauv cov xwm txheej hauv qab no:

1. Kev kho mob hnyav hypertriglyceridemia nrog lossis tsis muaj HDL cholesterol tsawg
2. sib xyaw hyperlipidemia thaum siv statin yog contraindicated lossis tsis zam,
3. sib xyaw hyperlipidemia hauv cov neeg uas muaj kev pheej hmoo siab ntawm kev tsim kab mob plawv, ntxiv rau kev kho statin, thaum triglycerides thiab cov roj cholesterol siab (HDL) tsis raug tswj kom txaus.

Lub active tshuaj ntawm kev npaj Lipanthyl Supra yog fenofibrate. Nws yog ib pawg ntawm cov tshuaj hu ua fibrates uas yog siv los txo qis lipids (cholesterol, triglycerides) hauv cov ntshav.

Nyeem:Nws nce cov cholesterol thiab ua kom lub cev puas tsuaj. Cov cawv no phem tshaj

Lipanthyl Supra - mechanism ntawm kev txiav txim

Fenofibrate, active tshuaj. Lipanthyl Supra yog ib qho derivative ntawm fibric acid, lipid hloov pauv cov nyhuv uas nyob rau hauv tib neeg yog ua tiav los ntawm kev ua kom muaj nuclear receptors ntawm α-type (PPARα, Peroxisome Proliferator Activated Receptor type α).

Los ntawm activating PPARα, fenofibrate nce lipolysis thiab tshem tawm cov ntshav triglyceride-nplua nuj atherogenic hais los ntawm activating lipoprotein lipase thiab txo cov zus tau tej cov apolipoprotein CIII.

Kev ua kom PPARα kuj ua rau muaj kev nce hauv kev sib txuas ntawm apolipoproteins AI thiab AII. Kev cuam tshuam ntawm fenofibrate ntawm lipoproteins ua rau txo qis qis thiab qis qis qis (VLDL thiab LDL) uas muaj apolipoprotein B thiab nce qib siab lipoprotein (HDL) feem ntau uas muaj apolipoproteins AI thiab AII.

Fenofibrate feem ntau yog tawm hauv cov zis. Nws raug tshem tawm tag nrho hauv 6 hnub. Fenofibrate feem ntau yog tawm hauv daim ntawv ntawm fenofibric acid thiab nws cov glucuronide derivatives.

Saib: Tag nrho cov roj cholesterol, LDL thiab HDL. Yuav txo cov roj cholesterol li cas?

Lipanthyl Supra - ntau npaum li cas

Ib txwm noj Lipanthyl Supra raws nraim li koj tus kws kho mob lossis tus kws muag tshuaj tau hais rau koj. Nrog koj tus kws kho mob lossis kws muag tshuaj yog tias koj tsis paub meej. Koj tus kws kho mob yuav txiav txim siab npaum li cas ntawm cov tshuaj nyob ntawm seb koj tus mob.

Ib ntsiav tshuaj Lipanthyl Supra yuav tsum tau nqos nrog ib khob dej. Kev npaj yuav tsum tau noj nrog pluas noj, vim tias qhov nqus ntawm cov tshuaj ntawm lub plab khoob yog qhov phem dua.

Kev noj tshuaj Lipanthyl Supra yog raws li hauv qab no.

Cov neeg laus

1. Qhov pom zoo koob tshuaj yog 1 160 mg / 215 mg film-coated ntsiav tshuaj txhua hnub.
2. Cov neeg uas tam sim no noj cov tshuaj ntsiav uas muaj 200 mg ntawm fenofibrate (1 ntsiav tshuaj ib hnub twg) tuaj yeem pib noj 1 ntsiav tshuaj ntawm 160 mg ib hnub twg yam tsis tau hloov tshuaj.

Cov neeg muaj lub raum tsis txaus

Hauv cov neeg uas lub raum tsis txaus, tus kws kho mob yuav txo qhov koob tshuaj. Thaum muaj kev cuam tshuam zoo li no, nrog koj tus kws kho mob lossis kws muag tshuaj. Hauv cov neeg uas muaj lub raum tsis txaus (creatinine clearance <20 ml / min), cov tshuaj yog contraindicated.

Neeg laus

Rau cov neeg laus uas tsis muaj lub raum tsis txaus, qhov pom zoo rau cov neeg laus noj yog.

Cov neeg muaj lub siab tsis ua haujlwm

Lipanthyl Supra tsis pom zoo vim tsis muaj cov ntaub ntawv kho mob hauv cov neeg uas muaj kab mob siab tsis txaus.

Siv rau menyuam yaus thiab tub ntxhais hluas

Kev siv Lipantil Supra hauv cov menyuam yaus thiab cov tub ntxhais hluas hnub nyoog qis dua 18 xyoo tsis pom zoo.

Lub editorial board pom zoo: Multiorgan tsis ua haujlwm - Multiorgan dysfunction syndrome (MODS)

Lipanthyl Supra - contraindications

Lub ntsiab contraindication rau kev siv ntawm Lipanthyl Supra yog hypersensitivity rau lub active tshuaj ntawm cov tshuaj los yog tshuaj pab. Tsis tas li ntawd, Lipanthyl Supra tsis pom zoo rau:

1. daim siab tsis ua haujlwm (xws li biliary cirrhosis thiab tsis tau piav qhia txog lub siab ua haujlwm ntev),
2. kab mob gallbladder,
3. mob raum tsis ua haujlwm (eGRF <30 ml / min / 1,73 m2),
4. mob ntev lossis mob pancreatitis tshwj tsis yog mob pancreatitis vim mob hypertriglyceridemia,
5. photosensitivity lossis phototoxic tshwm sim thaum siv fibrates lossis ketoprofen.

Cov poj niam cev xeeb tub thiab pub niam mis yuav tsum sab laj nrog kws kho mob ua ntej siv Lipanthyl Supra. Feem ntau, koj yuav tsum tsis txhob noj cov tshuaj no thaum cev xeeb tub thiab pub niam mis.

Lipanthyl Supra yuav tsum tsis txhob siv nyob rau hauv cov neeg uas muaj hypersensitive rau txiv laum huab xeeb, txiv laum huab xeeb roj, soy lecithin los yog derivatives vim muaj kev pheej hmoo ntawm hypersensitivity tshwm sim.

Lub editorial board pom zoo: Kev nce qib lipase thiab pancreatitis

Lipanthyl Supra - kev ceev faj

Tham nrog koj tus kws kho mob lossis kws muag tshuaj ua ntej noj Lipanthyl Supra 160 yog:

1. muaj teeb meem mob rau daim siab los sis lub raum
2. muaj o ntawm daim siab, cov tsos mob muaj xws li yellowing ntawm daim tawv nqaij thiab dawb ntawm ob lub qhov muag (jaundice) thiab nce qib ntawm daim siab enzymes (pom nyob rau hauv kev sim kuaj)
3. koj muaj cov thyroid caj pas tsis ua haujlwm (tso ua haujlwm ntawm cov thyroid caj pas).

Yog tias ib qho ntawm cov lus ceeb toom saum toj no siv rau koj (lossis yog tias koj tsis ntseeg), nrog koj tus kws kho mob lossis kws muag tshuaj ua ntej noj Lipanthyl Supra.

Lipanthyl Supra - cuam tshuam rau cov leeg

Thaum noj Lipanthyl Supra koj tuaj yeem ntsib cov leeg tsis txaus ntseeg lossis mob, mob leeg lossis tsis muaj zog thaum noj cov tshuaj no. Lipanthyl Supra tuaj yeem ua rau cov leeg mob uas tuaj yeem ua rau mob hnyav. Cov mob no tsis tshua muaj tab sis suav nrog cov leeg mob thiab tawg. Qhov no tuaj yeem ua rau lub raum puas lossis tuag taus.

Koj tus kws kho mob tuaj yeem kuaj ntshav los kuaj xyuas koj cov leeg nqaij ua ntej thiab tom qab pib kho. Qhov kev pheej hmoo ntawm cov nqaij ntshiv tej zaum yuav ntau dua hauv qee cov neeg mob. Thov qhia rau koj tus kws kho mob yog tias:

1. tus neeg mob muaj hnub nyoog tshaj 70 xyoo,
2. muaj kab mob hauv lub raum
3. muaj kab mob thyroid
4. koj lossis ib tus neeg hauv koj tsev neeg muaj kab mob qog nqaij hlav
5. tus neeg mob haus cawv ntau,
6. Koj tab tom noj tshuaj kom txo koj cov qib roj cholesterol hu ua statins, xws li simvastatin, atorvastatin, pravastatin, rosuvastatin lossis fluvastatin.
7. keeb kwm ntawm cov leeg nqaij thaum noj statins lossis fibrates xws li fenofibrate, bezafibrate lossis gemfibrozil.

Yog tias ib qho ntawm cov ntsiab lus saum toj no tshwm sim hauv tus neeg uas xav siv Lipanthyl Supra, sab laj nrog kws kho mob ua ntej noj tshuaj.

Kuj nyeem: Statins - kev ua, indications, contraindications, phiv

Lipanthyl Supra - kev sib cuam tshuam nrog lwm cov tshuaj

Ua ntej noj Lipanthyl Supra, qhia rau koj tus kws kho mob lossis kws muag tshuaj yog tias koj noj tshuaj xws li:

1. cov tshuaj anticoagulants coj los txo cov ntshav (xws li warfarin)
2. Lwm cov tshuaj siv los tswj cov ntshav rog (xws li statins lossis fibrates). Kev noj tshuaj statin tib lub sijhawm li Lipanthyl Supra tuaj yeem ua rau muaj kev pheej hmoo ntawm cov leeg nqaij.
3. Cov tshuaj los ntawm pawg tshuaj siv los kho cov ntshav qab zib (xws li rosiglitazone lossis pioglitazone) - cyclosporine (ib qho tshuaj tiv thaiv kab mob). 

Lipanthyl Supra - qhov tshwm sim tshwm sim

Feem ntau tshaj tawm cov kev mob tshwm sim nrog fenofibrate yog digestive, gastric lossis plab hnyuv.

Cov kev mob tshwm sim ib txwm muaj (tuaj yeem cuam tshuam txog 1 hauv 10 tus neeg):

1. raws plab,
2. mob plab,
3. flatulence nrog cua,
4. xeev siab,
5. ntuav,
6. nce qib ntawm daim siab enzymes hauv cov ntshav
7. nce qib ntawm homocysteine ​​​​hauv cov ntshav.

Qhov tshwm sim tsis zoo (tuaj yeem cuam tshuam txog 1 hauv 10 tus neeg):

1. mob taub hau,
2. cholelithiasis,
3. txo qis kev sib deev tsav,
4. ua pob khaus, khaus lossis khaus khaus
5. nce creatinine tawm los ntawm ob lub raum.