La progesterone yog ib tug cov tshuaj steroid uas plays lub luag haujlwm tseem ceeb tshwj xeeb thaum lub sijhawm teeb tsa thiab kev txhim kho ntawm a cev xeeb tub. Txawm li cas los xij, nws tseem ceeb heev txawm tias cev xeeb tub sab nraud, rau kev saib xyuas ntawm qhov chaw mos.

Nws yog tsuas yog tsim los ntawm ovary (nrog rau kev xeeb tub) thiab xuab moos (los ntawm lub hlis thib ob, noj los ntawm lub cev daj). Thaum cev xeeb tub, nws tso cai rau kev tsiv teb tsaws ntawm lub qe fertilized mus rau lub tsev menyuam, tom qab ntawd ua kom nws txoj kev cog qoob loo, thiab lwm yam.

Qib ntawm progesterone nyob rau hauv cov ntshav txawv thaum lub sij hawm cev xeeb tub. Nws yog qis thaum lub sij hawm follicular theem, nce sharply thaum lub sij hawm luteal theem, mus txog ib tug siab tshaj plaws 5 mus rau 10 hnub tom qab surge ntawm LH (lub luteinizing hormone, uas ua rau ovulation). Tus nqi ntawd txo qis, tshwj tsis yog thaum cev xeeb tub.

Hauv cov ntshav, progesterone circulates khi rau ntau yam proteins (transcortin, albumin thiab orosomucoid).

Qhov ntau npaum ntawm cov ntshav progesterone (progestéronémie ua) tuaj yeem ua tau hauv ntau qhov xwm txheej:

• nruab nrab ntawm 20^st thiab 23^st hnub ntawm kev coj khaub ncaws, los xyuas kom meej tias corpus luteum tsim cov nqi ntawm progesterone ib txwm, tsim nyog rau kev cog qoob loo ntawm cev xeeb tub (yog tias tsis ntseeg thaum rov nchuav menyuam)
• Thaum lub sij hawm thawj lub lim tiam ntawm cev xeeb tub, kom paub tseeb tias nws muaj kev vam meej (tus nqi yuav tsum nyob twj ywm)
• txhawm rau txheeb xyuas qhov ua tau zoo ntawm ovulation induction hauv kev kho mob pab tsim
• txhawm rau kuaj mob ectopic cev xeeb tub (ua ke nrog kev kuaj hCG), progesterone tom qab ntawd ua rau qis qis.
• nyob rau hauv cov ntaub ntawv ntawm kev pab kho mob procreation, rau nyob rau hauv vitro fertilization thiab embryo hloov, los yog rau kev pab cuam intrauterine inseminations (nws yog ib tug cim ntawm ovulation)

Kev kuaj ntshav yog nqa tawm ntawm tus qauv venous, feem ntau ntawm qhov khoov ntawm lub luj tshib. Tsis tas yuav tsum tau npaj, tab sis hnub tim ntawm lub sijhawm kawg lossis pib cev xeeb tub yuav tsum tau teev tseg.

Raws li kev qhia, cov ntshav ib txwm muaj progesterone Kev xeeb tub sab nraud yog tsawg dua 1,5 ng / mL thaum lub sijhawm follicular, nruab nrab ntawm 0,7 thiab 4 ng / mL thaum lub sijhawm ovulation ncov thiab nruab nrab ntawm 2 thiab 30 ng / mL thaum lub sij hawm luteal theem (xav txog qhov muaj qhov tshwm sim ntawm ovulation. corpus luteum).

Lawv txo qis ntawm cov lawm.

Thaum cev xeeb tub, ntawm 5st week ntawmpaum laus, lawv muaj txog 40 ng / mL thiab ncav cuag 200 ng / mL thaum kawg cev xeeb tub.

Thaum kuaj pom cov qib qis ntawm progesterone, tshwj xeeb tshaj yog nyob rau hauv ib tug poj niam uas xav xeeb tub, supplementation yuav raug txiav txim siab nyob rau hauv qhov thib ob ntawm lub voj voog.

Thaum kawg, nco ntsoov tias cov progestéronémie ua tej zaum yuav muaj ntau ntxiv nyob rau hauv ob peb pathologies, tshwj xeeb tshaj yog tej yam ntawm zes qe menyuam los yog adrenal qog los yog tej yam congenital deficits.

Tsuas yog tus kws kho mob thiaj li tuaj yeem txhais cov txiaj ntsig thiab kuaj mob, qee zaum nrog kev pab los ntawm kev kuaj ntxiv lossis kev tshuaj ntsuam xyuas.