La bilirubin cov yog ib tug xim tsis soluble nyob rau hauv dej ntawm daj xim, tshwm sim los ntawm degradation ntawmhemoglobin cov. Nws yog lub ntsiab dye ntawm bile. Nws yog tsim nyob rau hauv lub hlwb ntawm lub nqi thiab pob txha pob txha, thiab ces thauj los ntawm cov hlab ntsha los ntawm albumin mus rau lub siab. Thaum muaj nyob rau hauv daim siab, nws yog conjugated nrog gluconic acid thiab ua soluble hauv dej. Hauv cov hnyuv, conjugated bilirubin muab cov quav ua xim av.

Tus kws kho mob yuav xaj kom kuaj ntshav rau bilirubin yog tias nws xav tias, piv txwv li:

• kab mob siab hepatobiliary: cov xwm txheej uas cuam tshuam rau nplooj siab (mob kab mob siab tshaj plaws) thiab / lossis cov kua tsib
• hemolytic syndromes (tus cwj pwm los ntawm kev puas tsuaj ntawm cov qe ntshav liab)
• los yog jaundice ntawm tus me nyuam mos, kuj hu ua jaundice ntawm tus me nyuam mos

Rau kev kuaj bilirubin, kuaj ntshav yuav tsum tau ua, uas suav nrog kev kuaj ntshav venous. Nws raug pom zoo tias koj tsis txhob noj lossis haus tsawg kawg 4 teev ua ntej kuaj ntshav. Tus kws kho mob kuj tseem tuaj yeem hais kom tus neeg mob tsis txhob noj qee yam tshuaj uas tuaj yeem cuam tshuam cov txiaj ntsig ntawm kev sim bilirubin.

Tus nqi ntawm tag nrho cov bilirubin hauv cov ntshav yog ib txwm nyob nruab nrab ntawm 0,3 thiab 1,9 mg / dl (milligrams per deciliter). Tus nqi ntawm conjugated bilirubin (tseem hu ua direct bilirubin) feem ntau yog nyob nruab nrab ntawm 0 thiab 0,3 mg / dl. 

Nco ntsoov tias qhov kev hu ua ib txwm muaj txiaj ntsig ntawm bilirubin hauv cov ntshav yuav txawv nyob ntawm seb lub chaw kuaj mob ua cov tshuaj ntsuam xyuas.

Tsuas yog kws kho mob tuaj yeem txhais cov txiaj ntsig thiab muab kev kuaj mob rau koj.

Yog tias qib bilirubin siab, nws hu uahyperbilirubinemia.

Nws tuaj yeem yog:

• predominance ntawm daim ntawv dawb (los ntawm ntau lawm los yog tsis muaj conjugation):

- kev huam yuaj transfusionnels

- hemolytic anemias: tshuaj lom, tshuaj, parasitic hemolysis, thiab lwm yam.

- Gilbert tus kab mob (genetic abnormality ntawm bilirubin metabolism)

- jaundice ntawm tus menyuam mos

- Criggler-Najjar syndrome (kev cuam tshuam ntawm bilirubin metabolism)

• predominance ntawm daim ntawv conjugated (conjugated bilirubin raug tso tawm rau hauv kev ncig thaum txoj kev ib txwm ntawm excretion raug thaiv):

- mob gallstone

- mob qog noj ntshav (neoplasia)

- mob pancreatitis

- toxic hepatitis, cawv kab mob siab, kab mob siab viral

- cirrhosis

Ib qho txawv tshwj xeeb ntawm "daj daj nrog dawb bilirubin", uas yog vim muaj ntau dhau ntawm kev puas tsuaj ntawm cov qe ntshav liab (hemolysis) ntawm "jaundice nrog conjugated bilirubin", uas cuam tshuam rau cov kab mob biliary lossis kab mob siab.