Cov kab mob Klebsiella pneumoniae yog tus kab mob enterobacterium lub luag haujlwm rau ntau tus thiab kis mob hnyav, feem ntau yog nosocomial hauv Fab Kis. Ib tug xov tooj ntawm hom ntawm Klebsiella pneumoniae tau tsim ntau yam tshuaj tiv thaiv tshuaj tua kab mob.

Klebsiella pneumoniae, yav tas los hu ua Friedlander's pneumobacillus, yog enterobacterium, uas yog, gram-negative bacillus. Nws yog ib txwm muaj nyob hauv txoj hnyuv, hauv txoj hlab pa ntawm tib neeg thiab tsiaj txhu sov: nws tau hais tias yog cov kab mob sib kis.

Nws colonizes txog 30% ntawm cov tib neeg hauv kev zom thiab nasopharyngeal mucous membranes. Cov kab mob no tseem muaj nyob hauv dej, av, nroj tsuag thiab hmoov av (kis los ntawm cov quav). Nws tseem yog kab mob ua lub luag haujlwm rau ntau yam kab mob:

• mob ntsws o,
• septicemia,
• cov kab mob hauv cov zis,
• kab mob hauv plab,
• mob raum.

Hauv Tebchaws Europe, Klebsiella pneumoniae yog qhov ua rau muaj mob sib kis hauv zej zog (hauv nroog) hauv cov neeg tsis muaj zog (haus dej cawv, mob ntshav qab zib, cov neeg laus lossis cov uas raug mob los ntawm cov kab mob ua pa ntev) thiab tshwj xeeb yog nosocomial kab mob (cog lus hauv tsev kho mob) hauv cov neeg pw hauv tsev kho mob (mob ntsws, mob sepsis) thiab kis mob ntawm cov menyuam yug tshiab thiab cov neeg mob hauv chav saib xyuas hnyav).

Cov kab mob Klebsiella pneumoniae tshwj xeeb tshaj yog lees paub tias yog lub luag haujlwm rau nosocomial tso zis thiab mob hauv plab, mob sepsis, mob ntsws, thiab mob chaw phais mob. Kwv yees li 8% ntawm kev kis mob nosocomial hauv Tebchaws Europe thiab Tebchaws Meskas yog vim tus kab mob no. Kab mob Klebsiella pneumoniae feem ntau tshwm sim hauv cov chaw saib xyuas menyuam mos, tshwj xeeb yog hauv cov chaw saib xyuas mob hnyav thiab hauv cov menyuam yug ntxov.

Cov tsos mob ntawm tus kab mob Klebsiella pneumoniae dav dav

Cov tsos mob ntawm tus kab mob Klebsiella pneumoniae feem ntau yog cov kab mob loj heev:

• kub taub hau,
• mob,
• kev puas tsuaj ntawm qhov xwm txheej dav dav,
• ua daus no.

Cov tsos mob ntawm tus kab mob ua pa nrog Klebsiella pneumoniae

Cov tsos mob ntawm tus kab mob ua pa nrog Klebsiella pneumoniae feem ntau yog mob ntsws, nrog hnoos thiab hnoos, ntxiv rau ua npaws.

Cov tsos mob ntawm tus kab mob tso zis los ntawm Klebsiella pneumoniae

Cov tsos mob ntawm tus kab mob tso zis nrog Klebsiella pneumoniae suav nrog hlawv thiab mob thaum tso zis, hnov ​​tsw thiab pos huab, nquag nquag thiab xav tau tso zis sai sai, qee zaum xeev siab thiab ntuav.

Cov tsos mob ntawm tus mob meningitis tshwm sim los ntawm Klebsiella pneumoniae

Cov tsos mob ntawm Klebsiella pneumoniae meningitis (tsawg heev) yog:

• mob taub hau,
• ua npaws,
• hloov lub xeev ntawm kev nco qab,
• crises convulsive,
• septic poob siab.

Kev txheeb xyuas qhov tseeb ntawm tus kab mob Klebsiella pneumoniae yog raws kev cais tawm thiab txheeb xyuas tus kab mob los ntawm kev kuaj ntshav, tso zis, hnoos qeev, hnoos qeev los sis cov nqaij mos. Kev txheeb xyuas cov kab mob yuav tsum tau ua nrog kev ua tau zoo ntawm cov tshuaj tua kab mob.

Cov tshuaj tua kab mob yog ib qho txheej txheem kuaj sim uas ua rau nws muaj peev xwm ntsuas qhov ua tau zoo ntawm cov kab mob sib kis los cuam tshuam nrog ib lossis ntau yam tshuaj tua kab mob, uas zoo li tseem ceeb rau kab mob Klebsiella pneumoniae uas feem ntau tiv taus ntau yam tshuaj tua kab mob.

Cov kab mob Klebsiella pneumoniae zoo li lwm yam Enterobacteriaceae yog nqa los ntawm txhais tes, uas txhais tau hais tias cov kab mob no tuaj yeem sib kis tau los ntawm daim tawv nqaij los ntawm cov khoom muaj kab mob los yog cov kab mob. Hauv tsev kho mob, cov kab mob kis los ntawm ib tus neeg mob mus rau lwm tus los ntawm txhais tes ntawm cov neeg saib xyuas uas tuaj yeem nqa cov kab mob los ntawm ib tus neeg mob mus rau lwm tus.

Tawm sab nrauv tsev kho mob Klebsiella pneumoniae tuaj yeem kho hauv nroog nrog cephalosporin (piv txwv li ceftriaxone) lossis fluoroquinolone (piv txwv li levofloxacin).

Kab mob sib kis nrog Klebsiella pneumoniae raug kho nrog tshuaj tua kab mob. Lawv feem ntau kho nrog cephalosporins dav-spectrum thiab carbapenems (imipenem, meropenem, ertapenem), lossis txawm tias fluoroquinolones lossis aminoglycosides. Kev xaiv qhov tshuaj tua kab mob twg los tswj hwm tuaj yeem ua rau nyuaj vim tias tau txais kev tawm tsam.

Kab mob Klebsiellia pneumoniae tau tsim ntau yam tshuaj tiv thaiv tshuaj tua kab mob. Lub Koom Haum Saib Xyuas Kev Noj Qab Haus Huv Ntiaj Teb (WHO) cais cov kab mob no ntawm 12 "cov kab mob tseem ceeb" tiv taus tshuaj tua kab mob. Piv txwv li, Klebsiella pneumoniae tuaj yeem tsim cov enzyme, carbapenemase, uas txwv qhov cuam tshuam ntawm yuav luag txhua qhov kev hu ua broad spectrum antibiotics-lactam tshuaj tua kab mob.

Hauv qee lub tebchaws, tshuaj tua kab mob tsis muaj txiaj ntsig zoo rau ib nrab ntawm cov neeg mob kho rau K. mob ntsws. Tau txais kev tiv thaiv tshuaj tua kab mob kuj tseem muaj feem cuam tshuam rau lwm chav tshuaj xws li aminoglycosides.