Kev tshawb fawb tau ua kom muaj kev nce qib zoo hauv kev kho mob du lupus. Txawm li cas los xij, tsis muaj qhov kho tau zoo rau tus kab mob no. Cov tshuaj kho lub neej kom zoo los ntawm kev txo qhov mob ntawm cov tsos mob, txo qhov kev pheej hmoo ntawm teeb meem thiab ncua kev cia siab rau lub neej.

Qhov zoo tshaj, kev kho mob ntawm lupus nrog rau kev siv tshuaj tsawg li sai tau thiab rau lub sijhawm luv tshaj, txhawm rau ua kom cov nplaim taws tawg. Qee tus neeg tsis xav tau tshuaj, lwm tus siv nws tsuas yog xav tau lossis rau lub sijhawm luv (flare-ups), tab sis ntau tus neeg xav tau kev kho mob ntev.

Tshuaj kho mob

Cov tshuaj kho mob (tshuaj nonsteroidal anti-inflammatory). Acetaminophen (Tylenol®, Atosol®) thiab tshuaj tua kab mob²⁵ tom khw (ibuprofen, Advil®, lossis Motrin) tuaj yeem siv los txo qhov mob hauv cov pob qij txha, thaum lupus tsis hnyav heev lossis flare-ups tsis mob heev. Txawm li cas los xij, cov kws kho mob tsis pom zoo kom cov neeg uas muaj a mob hnyav heev noj tshuaj tom khw los ntawm lawv tus kheej. Cov tshuaj no tuaj yeem ua rau muaj kev pheej hmoo ntawm teeb meem los ntawm lupus, tshwj xeeb yog lub raum puas. Nws yuav siv sijhawm ib ntus txhawm rau nrhiav cov tshuaj tiv thaiv kom raug thiab kho qhov koob tshuaj nrog koj tus kws kho mob.

Corticosteroids. Corticosteroids, tshwj xeeb yog prednisone thiab methylprednisone, yog cov tshuaj tiv thaiv zoo tshaj plaws rau kev kho mob lupus, thaum tus kab mob cuam tshuam ob peb lub cev. Siv txij thaum xyoo 1960 tawm tsam lupus, prednisone (Deltasone®, Orasone®) tau dhau los ua cov tshuaj tseem ceeb rau kev txhim kho lub neej zoo ntawm cov neeg mob. Nws pab txo qhov mob thiab tswj cov tsos mob, tshwj xeeb tshaj yog nrog flare-ups. Txawm li cas los xij, cov tshuaj corticosteroids tau noj ntau npaum lossis ntau lub sijhawm ntev tuaj yeem ua rau muaj kab mob sib kisSab los, suav nrog qhov pib ua pob, hloov pauv lub siab, mob ntshav qab zib^25-26 , teeb meem pom kev (cataracts), nce ntshav siab thiab cov pob txha tsis muaj zog (pob txha). Cov koob tshuaj tau raug kho nrog kws kho mob kom thiaj li tau txais cov kev mob tshwm sim tsawg li sai tau. Hauv lub sijhawm luv, cov kev mob tshwm sim tseem ceeb ntawm corticosteroids yog qhov hnyav nce thiab o ntawm lub ntsej muag thiab lub cev (edema). Kev siv cov tshuaj calcium thiab vitamin D pab txo kev pheej hmoo ntawm txha pob txha.

Cov tshuaj nplaum thiab kev kho hauv zos. Qee zaum cov tawv nqaij raug kho nrog tshuaj pleev, feem ntau yog nrog corticosteroids.

Anti-malarial tshuaj. Hydroxychloroquine (Plaquenil®) thiab chloroquine (Aralen®) - cov tshuaj kuj tseem siv los kho malaria - muaj txiaj ntsig zoo hauv kev kho mob lupus thaum cov tshuaj anti-inflammatory nonsteroidal tsis txaus. Lawv txo qhov mob thiab o ntawm pob qij txha thiab pab kho pob khaus. Ib qho ntawm cov tshuaj no tuaj yeem siv los ntawm lub caij nplooj ntoo hlav los txog rau lub caij nplooj zeeg los tiv thaiv qhov pib ntawm qhov txhab ntawm daim tawv nqaij. hnub. Hydroxychloroquine kuj tseem siv ua qhov kev kho mob yooj yim los tiv thaiv kev rov qab los. Cov kev phiv loj ntawm cov tshuaj no yog mob plab thiab xeev siab.

Cov tshuaj tiv thaiv kab mob. Cov neeg sawv cev tiv thaiv kab mob txo qis kev ua haujlwm ntawm lub cev tiv thaiv kab mob tiv thaiv nws tus kheej lub cev thiab cov nqaij. Cov tshuaj muaj zog no tau siv me me ntawm cov neeg thaum prednisone tsis pab nrog cov tsos mob lossis thaum nws ua rau muaj kev phiv ntau dhau. Lawv xav tau thaum lub lupus cuam ​​tshuam rau kev ua haujlwm ntawm duav los yog system tshee. Feem ntau siv yog cyclophosphamide (Cytoxan®), azathioprine (Imuran®) thiab mycophenolate mofetil (Cellcept®). Hauv qee tus neeg mob, methotrexate (Folex®, Rheumatrex®) kuj tuaj yeem siv tau ntawm cov tshuaj qis raws li kev kho kho. Cov tshuaj no tseem muaj lawv cov kev phiv tshwm sim, qhov tseem ceeb tshaj plaws uas muaj feem cuam tshuam rau kev kis kab mob ntau dua thiab muaj kev pheej hmoo loj hlob ntawm mob qog noj ntshav. Ib yam tshuaj tshiab, belimumab (Benlysta) yuav muaj txiaj ntsig zoo rau qee tus mob lupus; nws cov kev mob tshwm sim yog xeev siab, raws plab thiab kub cev²⁵.

lwm yam

Immunoglobulin infusions. Immunoglobulin (tshuaj tiv thaiv kab mob) tau txais los ntawm cov ntshav ntawm cov neeg pub dawb. Nkag mus rau hauv cov hlab ntshav, lawv muaj cov tshuaj tiv thaiv kab mob vim tias lawv ib nrab ua rau cov kab mob autoantibodies, piv txwv li cov tshuaj tiv thaiv tsis txaus uas tig tawm tsam lub cev thiab koom nrog hauv lupus. Immunoglobulin infusions tau tshwj tseg rau cov neeg mob lupus tiv taus lwm yam kev kho, xws li corticosteroids.