Lub Rau Hli 4, 2010 - Kev siv cov tshuaj statins - ib tsev neeg ntawm cov tshuaj kom txo cov roj cholesterol hauv cov ntshav - tuaj yeem ua rau muaj ntau yam kev phiv cuam tshuam rau lub qhov muag, lub siab, lub raum thiab cov leeg.

Qhov no yog qhia los ntawm cov kws tshawb fawb Askiv uas tau txheeb xyuas cov ntaub ntawv ntawm ntau dua 2 lab tus neeg mob, 16% ntawm cov neeg tau lossis twb tau kho nrog statins.

Raws li cov ntaub ntawv khaws tseg, rau txhua txhua 10 tus neeg siv, noj statins tshaj 000 xyoo tiv thaiv 5 tus neeg mob plawv, thiab 271 tus neeg mob qog noj ntshav.

Txawm li cas los xij, nws tseem ua rau 307 tus neeg mob ntxiv rau cov kab mob cataracts, 74 tus neeg mob siab ua haujlwm tsis zoo, 39 tus neeg mob myopathy thiab 23 tus neeg mob ntxiv rau mob raum tsis ua haujlwm, ntxiv rau txhua 10 tus neeg siv tshuaj ntau dua 000 xyoo.

Cov kev mob tshwm sim no tshwm sim ntau zaus hauv cov txiv neej xws li poj niam, tshwj tsis yog myopathy - lossis cov leeg nqaij degeneration - uas cuam tshuam ze li ob zaug ntau tus txiv neej li poj niam.

Thiab yog tias cov kev mob tshwm sim no tshwm sim thoob plaws hauv 5 xyoo uas cov neeg mob tau ua raws, tshwj xeeb tshaj yog thaum lub sijhawm 1^re xyoo ntawm kev kho mob lawv feem ntau nquag.

Cov ntaub ntawv no siv rau txhua hom statins siv hauv txoj kev tshawb no, piv txwv li simvastatin (xws li 70% ntawm cov neeg koom), atorvastatin (22%), pravastatin (3,6%), rosuvastatin (1,9%) thiab fluvastatin (1,4. , XNUMX%).

Txawm li cas los xij, fluvastatin ua rau muaj teeb meem hauv siab ntau dua piv rau lwm pawg ntawm statins.

Raws li cov kws tshawb fawb, qhov kev tshawb fawb no yog ib qho ntawm ob peb los ntsuas qhov teeb meem ntawm qhov tshwm sim ntawm kev noj statins - feem ntau piv cov txiaj ntsig ntawm cov no ntawm kev txo qis kev pheej hmoo ntawm cov hlab plawv mus rau cov placebo.

Tsis tas li ntawd, lawv ntseeg hais tias cov teeb meem tau pom yuav tsum tsis txhob pom qhov txo qis ntawm 24% ntawm cov kab mob plawv uas noj tshuaj tau muab, nyob rau hauv lub moj khaum ntawm txoj kev tshawb no.

Mloog cov neeg mob ntau dua

Raws li cov kev mob tshwm sim tau teev tseg hauv txoj kev tshawb fawb no, cov kws tshawb fawb pom zoo kom cov kws kho mob ua raws li lawv cov neeg mob kom ceev nrooj xyuas cov kev mob tshwm sim uas yuav tshwm sim, kho lossis nres lawv cov tshuaj, yog tias tsim nyog.

Qhov no kuj yog qhov kev xav ntawm tus kws kho plawv Paul Poirier, tus thawj coj ntawm kev tiv thaiv kab mob plawv thiab kev kho mob ntawm lub plawv Institut de cardiologie thiab de pneumologie de Québec.

Nws tau hais tias "Qhov kev tshawb fawb no muab cov ntaub ntawv tiag tiag rau peb txog qhov tshwm sim ntawm qhov tshwm sim tsis zoo, thiab lawv hnyav," nws hais. Ntxiv mus, hauv tsev kho mob, thaum tus neeg mob kho nrog statins raug kev txom nyem los ntawm cov leeg nqaij dystrophy lossis mob siab, cov tshuaj raug tso tseg. “

Qhov kev pheej hmoo siab ntawm kev txom nyem los ntawm cataracts surprise Paul Poirier. "Cov ntaub ntawv no yog tshiab thiab nws tsis yog qhov tseem ceeb vim nws cuam tshuam rau cov neeg laus uas twb muaj mob lawm, uas yuav muaj kev pheej hmoo ntxiv rau qhov teeb meem ntxiv," nws hais ntxiv.

Raws li tus kws kho mob plawv, cov txiaj ntsig kuj yog ib qho kev ceeb toom rau cov teb chaws juggling lub tswv yim ntawm kev ua statins muaj yam tsis muaj tshuaj.

"Nws yog qhov tseeb tias kev siv statins yuav tsum tau saib xyuas thiab xav kom cov neeg mob tau txais kev ceeb toom txaus ntawm cov kev mob tshwm sim," ntxiv rau tus kws kho plawv.

Tab sis ntau tshaj qhov ntawd, UK txoj kev tshawb fawb ua haujlwm ceeb toom rau cov kws kho mob kho lawv cov neeg mob nrog statins.

"Ib statin yog ib yam tshuaj uas ua rau muaj kev pheej hmoo thiab peb yuav tsum ua raws li cov neeg mob zoo dua. Qhov tseem ceeb tshaj plaws, peb yuav tsum mloog thiab ntseeg tus neeg mob uas yws txog cov tsos mob, txawm tias cov no tsis tau teev nyob rau hauv cov ntaub ntawv tshawb fawb: tus neeg mob tsis yog ib qho kev txheeb cais lossis qhov nruab nrab thiab yuav tsum tau kho nyob rau hauv ib txoj kev tshwj xeeb ”, xaus lus D.^r Tsob ntoo.

Martin LaSalle - PasseportSanté.net

1. Hippisley-Cox J, thiab al, Tsis txhob xav txog qhov tshwm sim ntawm statins hauv cov txiv neej thiab poj niam hauv tebchaws Askiv thiab Wales: cov pej xeem raws li kev tshawb fawb nrog QResearch database, British Medical Journal, luam tawm online 20 May 2010,; 340: 2197 Ib.

2. Rosenberg H, Allard D, Prudence oblige: kev siv cov statins hauv cov poj niam, Kev Ua Haujlwm rau kev tiv thaiv kev noj qab haus huv ntawm cov poj niam, Lub Rau Hli 2007.