Acanthosis nigricans (AN) yog daim tawv nqaij uas pom tau los ntawm qhov tsaus ntuj, qhov tuab ntawm daim tawv nqaij nws ua rau, feem ntau yog nyob rau hauv cov quav ntawm lub caj dab thiab lub xub pwg. Cov kab mob dermatosis no feem ntau ua rau lub cev tsis zoo thiab cuam tshuam nrog kev rog, tab sis nws kuj tseem tuaj yeem yog lub cim qhia ntawm tus kab mob lwm yam xws li mob qog noj ntshav.

Cov tsos ntawm qhov tsaus ntuj, tuab, rougher thiab qhuav, tab sis tsis mob, thaj chaw ntawm daim tawv nqaij yog tus yam ntxwv ntawm Acanthosis nigricans. Lawv cov xim tshwm sim los ntawm hyperpigmentation (nce melanin) thiab tuab los ntawm hyperkeratosis (nce keratinization). Kev loj hlob zoo li wart tuaj yeem txhim kho. Cov pob me me no tuaj yeem tshwm sim ntawm txhua qhov ntawm lub cev, tab sis lawv muaj feem cuam tshuam rau cov tawv nqaij, ntawm qib ntawm caj dab, lub xub pwg, puab tais thiab qhov chaw genito-anal. Lawv pom me ntsis tsawg dua ntawm lub hauv caug, lub luj tshib, ob lub mis thiab ntaws. Kev txheeb xyuas tseeb yuav tsum txiav tawm qhov kev xav ntawm Addison tus kab mob [[+ txuas]] uas ua rau muaj haujlwm zoo sib xws.

Cov kws tshawb fawb xav tias acanthosis nigricans yog cov tshuaj tiv thaiv ntawm daim tawv nqaij ua rau cov tshuaj insulin ntau dhau, cov tshuaj tsim los ntawm tus txiav txiav uas tswj cov ntshav qabzib. Qhov kev tiv thaiv insulin no tuaj yeem cuam tshuam nrog ntau yam teeb meem, suav nrog kev rog thiab hom 2 mob ntshav qab zib. Hauv nws daim ntawv me, feem ntau thiab paub zoo li pseudoacanthosis nigricans, cov no yog cov tawv nqaij tshwm sim cuam tshuam nrog kev rog thiab thim rov qab nrog kev poob phaus. Cov tshuaj kuj tseem tuaj yeem ua rau qee kis, xws li cov tshuaj hormones loj hlob lossis qee yam tshuaj tiv thaiv qhov ncauj.

Acanthosis nigricans kuj tuaj yeem yog sab nrauv thiab pom pom ntawm qhov pib, tsis meej pem tsis meej pem. Daim ntawv phem no yog hmoov zoo ntau dua vim tias cov kab mob ua rau feem ntau hloov pauv mus ua qog: nws tau pom nyob hauv 1 ntawm 6 tus neeg mob qog noj ntshav, feem ntau cuam tshuam rau lub plab zom mov lossis cov kab mob genitourinary. -tso zis. Qhov nruab nrab lub neej kev cia siab ntawm tus neeg mob nrog malignant AN raug txo mus rau ob peb xyoos. (000)

Txiv neej thiab poj niam muaj kev txhawj xeeb sib npaug thiab acanthosis nigricans tuaj yeem tshwm ntawm txhua lub hnub nyoog, tab sis nyiam dua thaum laus. Nco tseg tias cov neeg tawv nqaij feem ntau cuam tshuam ntau, yog li qhov ua ntej ntawm NA yog 1-5% ntawm cov neeg dawb thiab 13% ntawm cov neeg tawv dub. (1) Qhov tshwm sim ntawm daim tawv nqaij no tau pom nyob hauv ib nrab ntawm cov neeg laus uas muaj rog rog hnyav.

Tus kab mob no tsis kis tau. Muaj cov xwm txheej hauv tsev neeg ntawm AN, nrog kev kis tus kheej sib kis (ua rau tus neeg cuam tshuam muaj 50% kev pheej hmoo kis tus kabmob rau lawv cov menyuam, ntxhais thiab tub).

Kev kho mob rau AN me cuam tshuam nrog txo qib insulin hauv cov ntshav nrog rau kev noj zaub mov tsim nyog, tshwj xeeb tshaj yog txij li AN tuaj yeem yog cim qhia txog ntshav qab zib. Nyob rau hauv txhua rooj plaub, nws yog qhov yuav tsum tau sab laj nrog kws kho mob tawv nqaij thaum pom qhov tshwm sim ntawm thaj tsam ntawm cov tawv nqaij tsaus thiab tuab. Thaum AN tshwm nyob rau hauv tus neeg uas tsis rog, yuav tsum tau tshuaj xyuas kom paub tseeb tias nws tsis cuam tshuam nrog qhov pib muaj qog.