Peb txhais covandropause zoo li txhua yam kev mob lub cev thiab lub hlwb uas tuaj yeem nrog tsawg testosterone nyob raucov txiv neej kev laus. Feem ntau nws yuav tshwm sim nyob ib puag ncig 45 rau 65.

Cov tsos mob no yog los ntawm txo kev sib deev tsis qab los thaum tuaj txog ntawm teeb meem erectile los ntawm qhov kev xav ntawm qhov tsis muaj zog thiab tsav tsheb. Lub sijhawm tawm hws ntau dhau, teeb meem nrog pw tsis tsaug zog thiab hnyav nce tuaj yeem ntxiv rau qhov cuam tshuam ntawm kev poob qis hauv kev tsim cov tshuaj hormones poj niam txiv neej.

Pom tias ua haujlwm tsis zoo los ntawm qee tus, raws li kev xav ntawm lub laus ib txwm los ntawm lwm tus, andropause tseem yog teeb meem. Dab tsi ntxiv, tsuas yog cov tshuaj muaj, testosterone, tsis tau muaj pov thawj, txawm hais txog kev ua tau zoo lossis kev nyab xeeb.

Muaj pes tsawg tus txiv neej cuam tshuam?

Txij li thaum lubandropause yog paub me ntsis thiab tsis tshua pom muaj, peb tsis muaj cov ntaub ntawv qhia meej ntawm kev faib ua feem ntawm cov txiv neej uas raug kev txom nyem los ntawm nws.

Txawm li cas los xij, raws li txoj kev tshawb fawb loj luam tawm xyoo 2010, European Male Aging Study, tsuas yog 2% txiv neej hnub nyoog 40 rau 80 tab tom muaj qhov mob ntshav qab zib: feem pua ​​yog 3% ntawm cov neeg hnub nyoog 60 txog 69 xyoos thiab 5% ntawm cov neeg hnub nyoog 70 txog 79 xyoos¹. Kev kuaj mob tau ua raws qhov muaj cov tsos mob ntawm andropause thiab qis dua li cov ntshav testosterone qib ib txwm muaj.

Cov txiaj ntsig no qhia tias kev kho tshuaj testosterone yog haum rau tsawg tus txiv neej, raws li txoj kev tshawb fawb sau ntawv.¹². Feem ntau, raws li lawv qhov kev soj ntsuam, cov tsos mob muaj feem cuam tshuam nrog kev laus, rog lossis lwm yam teeb meem kev noj qab haus huv. Qhov tseeb, 20% txog 40% ntawm cov txiv neej txhim kho Cov tsos mob yuav zoo ib yam li andropause nrog hnub nyoog¹¹.

Puas yog lo lus nug ntawm testosterone?

La testosterone yog muab raws li kev kho mob ntawmandropause rau me ntsis dhau kaum xyoo. Lub hom phiaj ntawm kev kho mob yog txhawm rau txhim kho lub neej zoo los ntawm kev txo cov tsos mob. Cov tuam txhab muag tshuaj sib cav tias testosterone kuj tseem tuaj yeem ncua cov txheej txheem ntawm laus : poob qis ntawm cov leeg nqaij thiab muaj kev pheej hmoo ntawm kev tawg, ntau qhov kev sib deev muaj zog, suav nrog kev txhim kho kom zoo dua, thiab lwm yam.

Nov yog lub hauv paus tseem ceeb uas ua rau kev kho mob andropause ib tug ncauj lus kom ntxaws thiab complex:

• Le testosterone qib uas qhia txog "kev tsis muaj peev xwm" hauv cov txiv neej nruab nrab tsis paub. Ib qho ntxiv, tus nqi no txawv ntawm txiv neej mus rau txiv neej. Cov nplai uas siv tam sim no muaj qhov tseem ceeb ntawm qhov tsis raug thiab raws li qhov nruab nrab tsim rau cov tub hluas;
• Tsis muaj Cov tsos mob tshwj xeeb rau andropause. Hauv lwm lo lus, txhua qhov tsos mob tshwm sim tuaj yeem yog qhov tshwm sim ntawm lwm yam teeb meem kev noj qab haus huv, xws li kev nyuaj siab, teeb meem vascular lossis rog dhau;
• Kev koom tes ntawm qis testosterone thiab cov tsos mob ntawm andropause tsis muaj zog, raws li kev tshawb fawb ntau yam. Cov txiv neej uas muaj qib testosterone ib txwm tuaj yeem pom cov tsos mob ntawm andropause. Qee cov kws tshaj lij ntseeg tias cov tsos mob andropause feem ntau tshwm sim los ntawm qhov tsis zoo cwj pwm ntawm lub neej^{2, 11};
• cov cov kev pab cuam thiab txaus ntshai kev kho nrog testosterone tsis tau hais meej meej los ntawm kev sim tshuaj, ob qho tib si luv thiab ntev. Qee tus kws tshaj lij hais tias kev kho tshuaj testosterone yog tsuas yog cov placebo kim¹². Qhov kev ntshai tseem ceeb nrog kev kho mob no rau cov txiv neej laus yog tias koj nce kev pheej hmoo mob qog noj ntshav lossis mob hlab ntsha tawg. Qhov no vim tias testosterone nce qib hemoglobin thiab tuaj yeem hloov pauv lipid profile hauv cov ntshav, ua rau muaj kev pheej hmoo ntawm cov ntshav khov ua rau hauv cov hlab ntshav hauv lub hlwb. Lwm qhov kev pheej hmoo hais txog suav nrog: kev puas tsuaj rau lub siab, kev txhim kho lub mis (uas tuaj yeem ua rau mob), mob qog noj ntshav, nce kev ua phem lossis tsis muaj kev sib raug zoo hauv lub cev thiab ua rau muaj kev tsis zoo noj qab haus huv tam sim no (pw tsaug zog apnea, mania, kev nyuaj siab, thiab lwm yam). Zoo li cov tshuaj hormones tau qhia rau cov poj niam tom qab cev xeeb tub, nws muaj peev xwm ua tau nyob rau tom qab tias qhov kev kho testosterone no ua rau muaj kev phom sij txaus ntshai. Kev kawm tseem tab tom kawm;
• Lwm yam kev hloov pauv hormonal tuaj yeem piav qhia qhov tshwm sim ntawm andropause. DHEA (dehydroepiandrosterone), kev loj hlob hormone, melatonin thiab, kom tsawg dua, cov thyroid hormones kuj ua rau lawv lub zog.

diagnostic

Kev kho mobandropause tsis ntev los no, cov txheej txheem coj mus rau kev kuaj mob tsis muaj lub hauv paus kev tshawb fawb ruaj khov.

Tus kws kho mob xub nug txog cov tsos mob tau hnov los ntawm nws tus neeg mob. Nws yuav siv qee cov ntawv ntsuas los piav qhia qhov ua tau zoo ntawm cov tsos mob, xws li kev xeem AMS (rau Laus Txiv Neej Qhab Nia) lossis xeem ADAM (rau Androgen Deficiency ntawm Tus Txiv Neej Laus). Txhawm rau saib cov kev xeem no, saib Cov Chaw Soj Ntsuam Zoo.

Nov yog lub sijhawm zoo los tsim kom muaj ua kom tiav kev kuaj mob : Kev kuaj ntshav (lipid profile, thyroid hormones, tshwj xeeb prostate antigen, thiab lwm yam), portrait ntawm kev noj qab haus huv ntawm cov hlab plawv, cov ntsiab lus ntawm kev ua neej nyob. Daim ntawv teev cov tshuaj thiab cov khoom noj qab haus huv uas tau noj yuav ua tiav daim duab. Qhov kev ntsuam xyuas no yuav pab kom tsis suav nrog lwm yam ua rau cov tsos mob xav tau (anemia, kev nyuaj siab, hypothyroidism, mob nkees nkees, teeb meem ntshav ncig, kev phiv tshuaj, thiab lwm yam).

Kev kuaj ntshav

Nov yog qee qhov kev piav qhia txog kev ntsuas uas tau siv los ntsuas seb puas muaj testosterone tsis txaus.

Raws li Lub Koom Haum Thoob Ntiaj Teb rau Kev Kawm ntawm Cov Txiv Neej Laus (ISSAM), kev ntsuas ntsuas ntsuas ntshav testosterone ntau ntau yuav tsum yog ib feem ntawm kev kuaj mob vim tias cov tsos mob yuav tsis cuam tshuam nrog andropause³. Tab sis cov kev ntsuas no tsuas yog ua yog tias ntau dua ib qho tsos mob tshwm sim.

• Tag nrho cov qib testosterone. Qhov txiaj ntsig ntawm qhov kev ntsuas no suav nrog ob qho tib si testosterone khi rau tus neeg thauj khoom (the kev sib deev hormone binding globuline lossis SHBG thiab, rau qhov tsawg dua, albumin) thiab testosterone uas nkag mus dawb hauv cov ntshav;
• Dawb qib testosterone. Qhov ntsuas no yog qhov tseem ceeb vim tias nws yog testosterone dawb uas ua haujlwm hauv lub cev. Qhov nruab nrab, kwv yees li 2% ntawm testosterone nkag mus dawb hauv cov ntshav. Tsis muaj kev sim uas ntsuas ncaj qha qib dawb testosterone. Yog li kws kho mob kwv yees los ntawm kev suav: lawv ntsuas tus nqi ntawm kev sib deev hormone binding globuline (SHBG) hauv cov ntshav thiab tom qab ntawd rho nws los ntawm qib testosterone tag nrho.