Ntau tshaj li tsib xyoos dhau los, cov kws tshawb fawb tau pom tias kev noj cov nqaij kib - nrog rau cov nqaij sib sib zog nqus kib, cov nqaij ci thiab cov nqaij barbecued - ua rau muaj kev pheej hmoo ntawm plab hnyuv loj heev.
Qhov no yog vim heterocyclic amines, uas tshwm sim nyob rau hauv cov nqaij overcooked, cuam tshuam cov metabolism hauv ib txwm. Txawm li cas los xij, raws li kev tshawb fawb kho mob tshiab, qhov xwm txheej nrog cov nqaij kib yog qhov phem dua li yav dhau los xav.
Ntxiv nrog rau mob qog noj ntshav, nws kuj ua rau mob ntshav qab zib thiab dementia, uas yog, nws yuav luag zoo tib yam rau lub cev raws li kev ua tiav, "tshuaj" thiab "ceev" zaub mov, lossis cov khoom noj uas tau ua tsis raug. Cov kws kho mob tau ntseeg tias qhov yuav tshwm sim ntawm cov kab mob loj heev, tsis tuaj yeem hloov pauv tau nce ncaj qha nrog ntau npaum li cas tus neeg noj cov zaub mov no - txawm tias nws yog burger ntim nrog cov khoom noj khoom haus los ntawm lub rooj noj mov lossis "zoo qub" tob-kib steak.
Txoj kev tshawb no tau ua los ntawm Icahn Tsev Kawm Ntawv ntawm Tshuaj hauv New York thiab luam tawm nyob rau hauv American scientific journal Proceedings of National Academy of Sciences. Cov txiaj ntsig tau pom tias cov nqaij kib hnyav heev (txawm yog lub lauj kaub kib lossis ci ci) ncaj qha cuam tshuam nrog lwm yam kab mob loj - Alzheimer's disease.
Hauv lawv daim ntawv tshaj tawm, cov kws kho mob tau piav qhia meej txog cov txheej txheem ntawm qhov zoo li AGEs thaum lub sij hawm kho cua sov ntawm cov nqaij, "Advanced Glicated End products" (Advanced Glicated End products, los yog AGE rau luv luv - "hnub nyoog"). Cov tshuaj no tseem tsis tau kawm me ntsis, tab sis cov kws tshawb fawb twb tau ntseeg tias lawv muaj kev phom sij heev rau lub cev thiab ua rau muaj kab mob loj heev, suav nrog Alzheimer's disease thiab senile dementia.
Cov kws tshawb fawb tau sim kuaj cov nas, ib pawg uas tau noj cov zaub mov siab hauv cov khoom siv glycation kawg, thiab lwm pab pawg tau noj cov zaub mov uas txo cov ntsiab lus ntawm cov teeb meem AGEs. Raws li qhov tshwm sim ntawm kev zom cov zaub mov "phem" hauv lub hlwb ntawm "nqaij noj" nas, muaj qhov pom pom ntawm kev puas tsuaj ntawm beta-amyloid protein - qhov taw qhia tseem ceeb ntawm kev mob Alzheimer's hauv tib neeg. Nyob rau tib lub sijhawm, lub cev ntawm cov nas uas noj cov zaub mov "zoo" tuaj yeem ua rau cov khoom tsim tawm ntawm cov khoom no thaum lub sij hawm assimilation ntawm zaub mov.
Lwm qhov ntawm txoj kev tshawb no tau ua rau cov neeg laus (tshaj 60 xyoo) uas muaj kev dementia. Kev sib raug zoo ncaj qha tau tsim los ntawm cov ntsiab lus ntawm AGEs hauv lub cev thiab qhov tsis muaj zog ntawm kev txawj ntse ntawm tus neeg, nrog rau kev pheej hmoo ntawm kab mob plawv. Dr. Helen Vlassara, uas yog tus thawj coj qhov kev sim, tau hais tias: “Peb qhov kev tshawb pom tau taw qhia rau txoj hauv kev yooj yim los txo txoj kev pheej hmoo ntawm cov kab mob no yog noj zaub mov qis hauv AGEs. Piv txwv li, qhov no yog cov khoom noj uas tsis muaj cua sov nrog dej ntau - ib txoj kev ua noj uas tau paub rau noob neej ntau pua xyoo.
Cov kws tshawb fawb tseem tau thov kom faib cov kab mob Alzheimer li "Hom XNUMX Ntshav Qab Zib" tam sim no. daim ntawv no ntawm dementia yog ncaj qha ntsig txog kev nce qib suab thaj hauv lub hlwb. Dr. Vlassara xaus lus: “Kev tshawb fawb ntxiv yog xav tau los tsim kom muaj kev sib txuas ntawm AGEs thiab ntau yam kab mob metabolic thiab neurological. (Rau tam sim no, ib yam tuaj yeem hais tau - Neeg tsis noj nqaij) ... los ntawm kev txo cov khoom noj muaj AGE-nplua nuj, peb ntxiv dag zog rau lub ntuj tiv thaiv kev tiv thaiv ob qho tib si Alzheimer's thiab ntshav qab zib. "
Ib qho laj thawj zoo rau kev xav rau cov neeg uas tseem xav txog qhov ua tau zoo "khoom noj qab haus huv", thiab tib lub sijhawm khaws lub peev xwm los xav txog kev xav!