Ib feem peb ntawm cov neeg mob tau kuaj pom tias mob qog noj ntshav hauv caj pas tau kis los ntawm tib neeg papillomavirus (HPV), feem ntau cuam tshuam nrog mob qog noj ntshav hauv tsev menyuam, tshaj tawm Phau Ntawv Xov Xwm ntawm Clinical Oncology.
Kev kis kab mob tib neeg papillomavirus (HPV) yog ib qho ntawm ntau tshaj plaws hauv ntiaj teb. Tus kab mob kis no feem ntau yog kev sib deev los ntawm kev sib cuag ncaj qha ntawm cov mucous daim nyias nyias ntawm qhov chaw mos, tab sis kuj ntawm daim tawv nqaij nyob ib ncig ntawm lawv. Lub Koom Haum Ntiaj Teb Kev Noj Qab Haus Huv (WHO) kwv yees tias txog li 80 feem pua. Cov neeg muaj kev sib deev sib deev muaj tus kab mob HPV nyob rau qee lub sijhawm hauv lawv lub neej. Rau feem ntau ntawm lawv, nws yog ib ntus. Txawm li cas los xij, hauv ib feem pua nws dhau los ua mob ntev, uas ua rau muaj kev pheej hmoo ntawm ntau hom mob qog noj ntshav.
Ntawm ntau tshaj 100 tus paub subtypes (hu ua serotypes) ntawm human papillomavirus (HPV), ob peb yog carcinogenic. Muaj ob hom subtypes - HPV16 thiab HPV18, uas yog lub luag haujlwm rau yuav luag 70 feem pua. mob qog noj ntshav.
WHO cov kws tshaj lij kwv yees tias tus kab mob HPV yog lub luag haujlwm rau yuav luag 100 feem pua. mob cancer ntawm lub ncauj tsev menyuam, thiab ntxiv rau 90 feem pua. Cov mob qog noj ntshav hauv qhov quav, 40 feem pua ntawm cov mob qog noj ntshav ntawm cov kab mob hauv nruab nrog cev - piv txwv li qhov chaw mos, qhov chaw mos thiab chaw mos, tab sis kuj rau qee feem pua ntawm cov qog nqaij hlav taub hau thiab caj dab, suav nrog 12% mob qog noj ntshav ntawm lub ntsws thiab pharynx thiab kwv yees li. 3 feem pua. mob qog noj ntshav ntawm qhov ncauj. Tseem muaj cov kev tshawb fawb qhia txog kev koom tes ntawm tus kab mob hauv kev txhim kho ntawm lub mis, mob ntsws thiab mob qog nqaij hlav prostate.
Cov kev tshawb fawb tsis ntev los no qhia tias muaj qhov tshwm sim ntawm caj pas thiab mob qog noj ntshav hauv kev sib txuas nrog tus kab mob HPV. Txog tam sim no, kev haus dej cawv thiab haus luam yeeb tau suav tias yog qhov tseem ceeb tshaj plaws uas muaj feem cuam tshuam rau cov qog nqaij hlav no. Cov kws tshawb fawb xav tias qhov nce hauv HPV kev koom tes hauv kev txhim kho cov qog nqaij hlav no cuam tshuam nrog kev ywj pheej ntawm kev sib deev ntau dua thiab kev nyiam ntawm qhov ncauj.
Txhawm rau kuaj kev sib raug zoo ntawm HPV thiab mob qog noj ntshav ntawm qee lub taub hau thiab caj dab, cov kws tshawb fawb los ntawm pab pawg thoob ntiaj teb tau tshawb fawb txog 638 tus neeg mob uas raug mob los ntawm lawv, suav nrog mob qog noj ntshav ntawm qhov ncauj (180 tus neeg mob), mob qog noj ntshav ntawm oropharynx (135 tus neeg mob) , mob qog noj ntshav ntawm qis pharynx / larynx (247 tus neeg mob). Lawv kuj tau tshuaj xyuas cov neeg mob qog noj ntshav (300 tus neeg). Rau kev sib piv, 1600 tus neeg noj qab haus huv tau sim. Lawv txhua tus tau koom nrog hauv kev tshawb fawb nyob sab Europe ntev txog kev sib raug zoo ntawm txoj kev ua neej thiab kev pheej hmoo mob qog noj ntshav - European Kev Tshawb Fawb Txog Kev Tshawb Fawb Txog Kev Kho Mob thiab Khoom Noj.
Cov ntshav kuaj uas tau pub dawb thaum pib ntawm txoj kev tshawb fawb thaum lawv noj qab nyob zoo tau txheeb xyuas cov tshuaj tiv thaiv kab mob rau HPV16 cov protein thiab lwm cov kab mob carcinogenic human papillomavirus subtypes xws li HPV18, HPV31, HPV33, HPV45, HPV52, thiab HPV6 thiab HPV11 uas yog cov feem ntau ua rau benign tab sis muaj teeb meem ntawm qhov chaw mos pob khaus (hu ua qhov chaw mos warts), thiab tsis tshua muaj peev xwm ua rau mob qog noj ntshav.
Cov qauv kuaj mob qog noj ntshav tau nyob nruab nrab ntawm 10 xyoo, tab sis qee qhov tseem muaj hnub nyoog tshaj XNUMX xyoo ua ntej kuaj mob.
Nws muab tawm tias ntau li 35 feem pua. Cov neeg mob qog noj ntshav Oropharyngeal tau pom tias muaj cov tshuaj tiv thaiv rau cov protein tseem ceeb ntawm HPV 16, luv luv li E6. Nws hloov tawm cov protein ua lub luag haujlwm rau inhibiting cov txheej txheem neoplastic hauv hlwb thiab yog li pab txhawb rau nws txoj kev loj hlob. Lub xub ntiag ntawm cov tshuaj tiv thaiv rau E6 protein nyob rau hauv cov ntshav feem ntau qhia txog kev loj hlob ntawm mob qog noj ntshav.
Rau kev sib piv, hauv pawg tswj hwm qhov feem pua ntawm cov neeg muaj cov tshuaj tiv thaiv kab mob hauv cov ntshav yog 0.6%. Tsis muaj kev sib raug zoo ntawm lawv lub xub ntiag thiab lwm cov qog nqaij hlav taub hau thiab caj dab suav nrog hauv txoj kev tshawb no.
Cov kws tshawb fawb tau hais tias kev sib raug zoo ntawm qhov muaj cov tshuaj tiv thaiv kab mob no thiab mob qog noj ntshav oropharyngeal muaj nyob txawm tias cov neeg mob los ntawm cov ntshav kuaj tau ntau dua 10 xyoo ua ntej kuaj mob qog noj ntshav.
Qhov zoo siab, ntawm cov neeg mob uas muaj mob qog noj ntshav oropharyngeal thiab muaj cov tshuaj tiv thaiv HPV16, qhov feem pua ntawm cov neeg tuag tsawg dua vim muaj ntau yam ua rau pom dua li cov neeg mob uas tsis muaj tshuaj tiv thaiv. Tsib xyoos tom qab kuaj mob, 84 feem pua tseem muaj sia nyob. cov neeg los ntawm thawj pab pawg thiab 58 feem pua. lwm tus.
Cov txiaj ntsig xav tsis thoob no muab qee cov pov thawj tias tus kab mob HPV16 tuaj yeem ua rau mob qog noj ntshav oropharyngeal, cov lus kws sau ntawv Dr. Ruth Travis ntawm University of Oxford.
Sara Hiom los ntawm Cancer Research UK lub hauv paus tau hais hauv kev xam phaj nrog BBC tias cov kab mob HPV muaj ntau heev.
Kev sib deev tsis zoo yuav ua rau muaj kev pheej hmoo kis tus kab mob los yog kis tus kab mob HPV rau lwm tus, tab sis cov hnab looj tes yuav tsis tiv thaiv koj los ntawm kev kis kab mob, nws tau sau tseg. Nws paub tias tus kab mob muaj nyob rau ntawm daim tawv nqaij ntawm qhov chaw mos kuj tuaj yeem ua rau kis kab mob.
Hiom tau hais tias nws tsis paub tias cov tshuaj tiv thaiv tam sim no siv los tiv thaiv qog noj ntshav hauv cov menyuam ntxhais hluas (ib tug ntawm lawv kuj tau pom zoo rau cov tub hluas los tiv thaiv qhov chaw mos thiab mob qog noj ntshav) tuaj yeem txo qhov kev pheej hmoo ntawm mob qog noj ntshav oropharyngeal. Yog tias qhov kev tshawb fawb tau lees paub qhov no, nws yuav pom tias lawv tuaj yeem siv tau ntau dua hauv kev tiv thaiv malignant neoplasms. (PAP)
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