Le phosphorus yog ib tug ntxhia qhov tseem ceeb rau ntau cov tshuaj tiv thaiv cellular, tshwj xeeb tshaj yog rau cov txheej txheem lub zog ntawm cov leeg nqaij. Phosphorus kuj ua lub luag haujlwm hauv mineralization ntawm cov nqaij pob txha, zoo li cov calcium.

Kwv yees li 85% ntawm phosphorus tau muab tso rau hauv cov pob txha. Ntshav phosphorus, uas pom nyob rau hauv daim ntawv ntawm monosodium lossis disodium phosphate, tshwj xeeb, sawv cev tsuas yog 1% ntawm tag nrho cov phosphorus.

Muaj ntau yam cuam tshuam nrog kev tswj hwm qib phosphorus hauv cov ntshav (phosphoremia), uas:

• qib vitamin D (nce kev nqus)
• parathyroid hormone (nce kev nqus thiab lub raum tso tawm)
• kev loj hlob hormone (txhawb kev zom zaub mov)
• corticosteroids (nce kev tso tawm)

Cov ntshav phosphorus ntau npaum tau qhia nyob rau hauv rooj plaub mob pob txha lossis hauv cov neeg pw hauv tsev kho mob, uas muaj teeb meem phosphoremia nquag.

Qhov ntau npaum li cas ntawm phosphorus ib txwm cuam tshuam nrog cov calcium (mob ntshav qab zib) thiab ib txhia neeg tsim tswv (ntshav creatinine).

Qhov tseeb, kev txiav txim siab ntawm qib calcium yuav tso cai rau tus kws kho mob txhawm rau txheeb xyuas a hyperparathyrodie (uas tseem ua rau nce ntxiv hauv cov calcium calcium).

Le noj tshuaj phosphorus tau los ntawm cov qauv ntshav, los ntawm a txoj hlab ntshav feem ntau yog nyob rau ntawm lub luj tshib.

Kev tso zis ntau npaum li cas (phosphaturie) kuj tseem tuaj yeem ua tau: hauv qhov no, tag nrho cov zis yuav tsum tau sau ntau dua 24 teev. Qhov koob tshuaj no yuav xav tau thaum muaj teeb meem ntawm lub raum, xav tias muaj teeb meem ntawm cov qog parathyroid thiab ntawm cov pob txha tsis meej.

Nws feem ntau tau qhia thaum cov txiaj ntsig ntawm kev ntsuas ntshav qhia tias qis phosphoremia, txhawm rau kho qhov kev kuaj mob.

Raws li phau ntawv qhia, cov ntshav phosphorus ntau nyob nruab nrab ntawm 0,8 txog 1,5 mmol / L lossis 25 thiab 45 mg / L. Hauv cov menyuam yaus, lawv nyob nruab nrab ntawm 1,5 txog 2 mmol / L.

Kev txo qis hauv qib phosphorus hauv cov ntshav yog hu ua kev mob hypophosphatemia ; hu ua nce ntxiv hyperphosphoric tshuaj.

Thaum cov ntshav thiab cov zis phosphorus qis (phosphaturia tsawg dua 10 mmoL / 24 h), hypophosphatemia feem ntau txuas nrog cov teeb meem zom zaub mov: malabsorption, noj tshuaj antacids, haus dej cawv ntev.

Thaum, ntawm qhov tsis sib xws, phosphaturia siab, nws muaj peev xwm ua rau tus neeg raug kev txom nyem los ntawm phosphorus lossis phosphate diabetes (poob phosphorus hauv cov zis). Tom qab ntawv yuav tsum kuaj ntxiv.

Hypophosphatemia feem ntau tshwm sim hauv cov neeg mob hauv tsev kho mob (1 txog 3%) thiab tshwj xeeb hauv cov neeg mob hnyav (30 txog 40%).

Hyperphosphatemia, ntawm qhov tod tes, yog qhov ua rau muaj teeb meem ntawm lub raum tsis ua haujlwm ntev. Txij li qhov txawv txav hauv qib phosphorus hauv cov ntshav tuaj yeem ua rau ntau yam mob plawv, ua pa lossis mob leeg, nws yog qhov tseem ceeb kom kuaj thiab kho lawv sai.