Txhais kev kho PUVA 

PUVA kev kho mob sib xyaw ua ke raug rau ib qho khoom siv hluav taws xob ntawm UVA hluav taws xob nrog kev kho mob raws li psoralen, UV sensitizing khoom. Li no lub ntsiab lus PUVA: P xa mus rau Psoralen thiab UVA rau ultraviolet rays A.

Lub ntsiab cai

Kev raug UVA yuav ua rau lub zais ntawm cov tshuaj hu ua cytokines, uas yuav muaj ob yam haujlwm:

• ib tug thiaj li hu ua antimitotic kev txiav txim, uas yuav ua rau qeeb proliferation ntawm epidermal hlwb;
• ib qho tshuaj tiv thaiv kab mob, uas yuav ua kom cov mob o.

Lub ntsiab lus qhia rau PUVA-kev kho yog kev kho mob ntawm psoriasis vulgaris hnyav (tee, medallions lossis thaj ua rau thaj) kis mus rau thaj chaw loj ntawm daim tawv nqaij.

Raws li kev ceeb toom, psoriasis yog ib qho kab mob ntawm daim tawv nqaij vim kev rov ua dua tshiab ntawm cov hlwb ntawm cov epidermis, keratinocytes. Raws li daim tawv nqaij tsis muaj sijhawm los tshem tawm nws tus kheej, cov epidermis thickens, cov nplais sib sau thiab tawm tuaj, tawm hauv daim tawv nqaij liab thiab o. Los ntawm calming o thiab slows lub proliferation ntawm epidermal hlwb, PUVAtherapy pab txo psoriasis plaques thiab qhov chaw tawm flare-ups.

Lwm cov kev qhia muaj nyob:

• atopic dermatitis thaum muaj kev sib kis tseem ceeb heev thiab tiv taus kev saib xyuas hauv zos;
• Thaum ntxov theem cutaneous lymphomas;
• photodermatoses, xws li lub caij ntuj sov lucitis piv txwv li, thaum lub photoprotective kev kho mob thiab lub hnub tiv thaiv tsis txaus;
• polycythemia pruritus;
• daim tawv nqaij lichen planus;
• Qee qhov mob hnyav alopecia areata.

Tus kws tshaj lij

Cov PUVA-kev kho mob yog muab los ntawm kws kho mob dermatologist thiab muab tso rau hauv ib qho chaw ua hauj lwm los yog nyob rau hauv lub tsev kho mob uas muaj irradiation cabin. Lawv raug them los ntawm Social Security tom qab lees txais qhov kev thov kom pom zoo ua ntej.

Kev kawm ntawm ib qho kev sib kho

Nws yog ib qho tseem ceeb tsis txhob siv dab tsi rau ntawm daim tawv nqaij ua ntej kev sib kho. Ob teev ua ntej, tus neeg mob siv psoralen los ntawm lub qhov ncauj, los yog tsis tshua muaj tshuaj pleev ib ce, los ntawm immersing ib feem ntawm lub cev los yog tag nrho lub cev nyob rau hauv ib tug aqueous tov ntawm psoralen (balneoPUVA). Psoralen yog ib tug photosensitizing tus neeg sawv cev ua rau nws muaj peev xwm ua kom cov hauj lwm zoo ntawm UV kho.

UVA tuaj yeem siv tau thoob plaws lub cev lossis hauv zos (tes thiab ko taw). Kev sib kho yuav kav li ntawm 2 mus rau 15 feeb. Tus neeg mob liab qab, tshwj tsis yog qhov chaw mos, thiab yuav tsum hnav tsom iav tsaus nti kom tiv thaiv lawv tus kheej los ntawm UVA rays.

Tom qab kev sib kho, nws yog ib qho tseem ceeb uas yuav tsum hnav looj tsom iav dub thiab tsis txhob raug tshav ntuj ntev li 6 teev.

Qhov zaus ntawm cov kev sib tham, lawv lub sijhawm thiab qhov kev kho mob yog txiav txim los ntawm tus kws kho mob dermatologist. Qhov kev sib dhos ntawm cov kev sib tham feem ntau yog ob peb zaug hauv ib lub lis piam (feem ntau 3 zaug sib nrug 48 teev), xa cov tshuaj maj mam nce ntxiv ntawm UV. Kwv yees li 30 ntu yuav tsum tau txais cov txiaj ntsig xav tau.

Nws tuaj yeem ua ke nrog kev kho PUVA nrog lwm txoj kev kho mob: corticosteroids, calcipotriol, retinoids (re-PUVA).

Contraindications

Kev kho PUVA yog contraindicated:

• thaum cev xeeb tub thiab lactation;
• nyob rau hauv cov xwm txheej ntawm kev siv cov tshuaj photosensitizing;
• lub siab thiab lub raum tsis ua haujlwm;
• daim tawv nqaij mob tshwm sim los yog aggravated los ntawm ultraviolet lub teeb;
• mob qog noj ntshav;
• kev puas tsuaj rau lub anterior chamber ntawm lub qhov muag;
• mob mob.

Phiv thiab txaus ntshai

Qhov kev pheej hmoo tseem ceeb, nyob rau hauv qhov xwm txheej ntawm ntau qhov kev kho PUVA, yog ntawm kev tsim mob qog noj ntshav. Qhov kev pheej hmoo no tau kwv yees tias yuav nce ntxiv thaum tus naj npawb ntawm cov kev sib tham, ua ke, ntau dua 200-250. Tsis tas li ua ntej muab tshuaj, tus kws kho mob dermatologist ua tiav kev ntsuam xyuas ntawm daim tawv nqaij txhawm rau txheeb xyuas tus neeg mob qhov kev pheej hmoo ntawm kev mob qog noj ntshav ntawm daim tawv nqaij (tus kheej keeb kwm ntawm mob qog noj ntshav, yav dhau los raug rau X-rays, muaj cov kab mob ua ntej ntawm daim tawv nqaij, thiab lwm yam). Nyob rau tib lub sij hawm, txhua xyoo dermatological xyuas yog pom zoo nyob rau hauv cov neeg uas tau txais ntau tshaj li 150 Phototherapy zaug, nyob rau hauv kev txiav txim mus ntes precancerous txhab los yog thaum ntxov cancer nyob rau ntawm ib thaum ntxov rau theem.

Kev mob me me yog nquag pom:

• xeev siab vim noj Psoralen;
• daim tawv nqaij dryness yuav tsum tau daim ntawv thov ntawm ib tug emollient;
• qhov nce hauv cov plaub hau uas yuav ploj mus thaum lub sijhawm nres.