LDH xaiv chav kawm ntawm cov enzymes, Lactase dehydrogenases. Lawv tau pom nyob txhua qhov chaw hauv lub cev, txawm nyob hauv cov leeg (thiab txawm tias lub plawv), hauv cov nqaij ntawm lub ntsws lossis hauv cov ntshav. Ib qho enzyme yog cov protein uas nws lub luag haujlwm yog txhawm rau ua kom muaj kev cuam tshuam hauv lub cev, hauv lwm lo lus kom ua rau lawv lossis ua kom cov txheej txheem uas feem ntau qeeb heev.

Muaj ntau hom, lossis isoenzymes, sau los ntawm tus lej raws li lawv qhov chaw nyob. Yog li cov ntawm lub plawv lossis lub hlwb tau txais cov xwm txheej ntawm LDH 1 thiab 2, thaum cov platelets thiab cov qog ntshav yog LDH3, cov ntawm lub siab LDH 4 thiab cov tawv nqaij LDH5.

Lub luag haujlwm ntawm LDH hauv lub cev yog txhawm rau hloov pauv ntawm pyruvate rau hauv lactate, thiab hloov pauv. Ob cov kua qaub no muaj lub luag haujlwm hloov pauv lub zog ntawm cov cell.

Nco ntsoov tias nws tseem hu ua lactate dehydrogenase, lossis lactic dehydrogenase, thiab qee zaum yog cim los ntawm LD.

Kev txaus siab kho mob ntawm LDH enzymes yog qhov tseem ceeb tshaj txhawm rau txheeb xyuas qhov txawv txav hauv lawv qhov muaj. Feem ntau, LDH raug khaws cia hauv lub cev lub cev. Tab sis yog tias cov ntaub so ntswg puas, lawv yuav nchuav, thiab yog li catalyze ntau thiab ntau pyruvate rau hauv lactate.

Kev txheeb xyuas lawv hauv cov cheeb tsam tshwj xeeb lossis tshuaj xyuas lawv tus cwj pwm hauv lub cev tuaj yeem ua rau nws txiav txim siab thaj chaw uas tau raug kev puas tsuaj ntawm tes, lossis ntsuas nws qhov hnyav. Nws kuj tseem muaj txiaj ntsig txhawm rau txheeb xyuas ntau yam mob, suav txij ntshav tsis txaus rau mob qog noj ntshav (saib "Kev txhais ntawm LDH qhov tshwm sim").

Kev tshuaj xyuas LDH ntau npaum li cas yog ua los ntawm kev kuaj ntshav yooj yim. Tshwj xeeb tshaj yog, lub chaw soj nstuam yuav tshuaj xyuas cov ntshav, cov kua uas muaj cov ntshav sib xws xws li cov qe ntshav liab da dej. Txawm hais tias tom kawg kuj tseem muaj LDH cov enzymes hauv lawv lub siab, nws yog qhov siab tshaj txhua qhov koob tshuaj uas suav hauv kev txiav txim siab seb qib twg txawv txav lossis tsis yog.

Tus nqi siv rau kev tshuaj xyuas ntawm LDH enzyme tau ntsuas ntawm 120 txog 246 U / L (units ib litre).

Txhawm rau taug qab qhov kev tshuaj xyuas, tus kws kho mob tuaj yeem tshuaj xyuas cov txiaj ntsig tau los ntawm lub chaw kuaj mob, thiab tej zaum tuaj yeem txheeb xyuas ntau yam teeb meem hauv tus neeg mob. Feem ntau, nws yuav tsum tau koom nrog qhov txiaj ntsig no nrog qib ntawm lwm cov enzymes lossis cov kua qaub, vim qhov yooj yim nce lossis txo qis ntawm LDH tuaj yeem muaj ntau lub hauv paus. Yog li muaj peev xwm sib txawv ntawm kev txhais lus.

Yog tias qib LDH siab:

• anemia

Feem ntau nws tuaj yeem ua rau mob hnyav (tseem hu ua Biermer's disease), lossis hemolytic anemia. Hauv qhov kawg, autoantibodies txuas rau cov qe ntshav liab thiab rhuav tshem lawv, uas nce qib LDH hauv cov ntshav.

• Cancers: Qee hom mob qog noj ntshav xws li neoplasias kuj tseem cuam tshuam nrog kev nce qib sai hauv LDH.
• Infarction: Ua raws li cov kab mob myocardial infarction, cuam tshuam nrog kev puas tsuaj rau cov nqaij ntawm lub plawv, kev nce qib LDH tau pom hauv 10 teev. Tus nqi ntawd poob qis dua hauv ob lub lis piam tom ntej.
• AVC (tib lub ntsiab lus zoo li infactus)
• Kev mob caj dab
• Mob raum thiab mob plab
• Mononucleosis
• Pulmonary embolism
• mob angina pectoris
• Npag dystrophy
• Kab mob siab (tshuaj lom lossis muaj teeb meem)
• Myopathy (nyob ntawm qhov chaw muaj teeb meem)

Yog tias qib LDH qis lossis ib txwm muaj:

Hauv qhov no nws yog qhov tsis muaj teeb meem tam sim no, lossis txheeb xyuas tau los ntawm qhov no txhais tau tias, hauv lub cev.

Tsis txhob txhawj xeeb: Thaum cov npe kab mob no tuaj yeem ntshai cov neeg uas tau txais txiaj ntsig LDH siab, nws yog qhov zoo kom nco ntsoov tias lwm yam kev ua si hauv ntiaj teb, xws li kev tawm dag zog, tuaj yeem ua rau nce ib ntus hauv LDH. hauv cov ntshav.

Hloov pauv, hemolysis (tawg ntawm cov qe ntshav liab hauv cov ntshav) thaum lub sijhawm kuaj tuaj yeem ua rau muaj qhov tsis zoo. LDH tam sim no hauv cov qe ntshav liab yuav kis mus rau qhov tseeb, thiab yog li ntawd cuam tshuam qhov tshwm sim.

Tom qab kuaj xyuas qib LDH, cov txiaj ntsig yuav raug xa mus rau koj tus kws kho mob uas tuaj yeem tham nrog lawv dua yog tias tsim nyog. Yog tias cov txiaj ntsig qhia pom tias muaj teeb meem, ces koj yuav raug xa mus rau tus kws tshaj lij tshwj xeeb hauv nqe lus nug.

Thaum muaj mob qog noj ntshav, kev saib xyuas tas li ntawm qib LDH tuaj yeem ua pov thawj tias yog lossis tsis yog mob qog noj ntshav tau ua tiav, txhawm rau paub seb lub hom phiaj ntawm lub hlwb puas tau puas tsuaj lossis seb lawv puas tua lwm qhov hauv lub cev.